anti-NMDA receptor autoantibody

Also Known As:

Anti-NMDAR autoantibody; NMDA receptor autoantibody; NMDAR autoantibody; anti-N-methyl-D-aspartate receptor autoantibody

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Autoantibodies: 35785
        anti-NMDA receptor autoantibody: 11
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Autoantibodies: 35785
        anti-NMDA receptor autoantibody: 11
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Autoantibodies: 35785
        anti-NMDA receptor autoantibody: 11

Experts

1.	Groc, Laurent: 2 articles (01/2018 - 01/2017)
2.	Honnorat, Jérôme: 2 articles (01/2018 - 01/2017)
3.	Leboyer, Marion: 2 articles (01/2018 - 01/2017)
4.	Chen, Tun-Chieh: 1 article (09/2022)
5.	Liang, Chih-Wei: 1 article (09/2022)
6.	Al-Diwani, Adam: 1 article (01/2022)
7.	Browne, Molly: 1 article (01/2022)
8.	Bull, Joshua: 1 article (01/2022)
9.	Campo, Leticia: 1 article (01/2022)
10.	Dale, Russell C: 1 article (01/2022)

Related Diseases

1.	Anti-N-Methyl-D-Aspartate Receptor Encephalitis 01/01/2020 - "To report an unexpectedly low rate of NMDAR autoantibody detection in serum from patients with anti-NMDAR encephalitis tested using a commercially available diagnostic kit in an exemplar clinical laboratory. " 12/15/2013 - "We measured anti-N-methyl-D-aspartate receptor (NMDAR) autoantibody levels and assessed B cell subsets using multicolor flow cytometry of peripheral blood mononuclear cells (PBMCs) from a recurrent anti-NMDAR encephalitis case to evaluate the effectiveness of rituximab treatment. "
2.	Autoimmune Diseases of the Nervous System 09/01/2022 - "Possessing anti-N-methyl-D-aspartate (NMDA) receptor autoantibody is the leading cause of autoimmune encephalitis. " 01/01/2018 - "The presence of anti-NMDA receptor autoantibody can cause various neuropsychiatric symptoms in the affected patients, termed anti-NMDA receptor autoimmune encephalitis. "
3.	Psychotic Disorders (Schizoaffective Disorder) 01/01/2018 - "Molecular Pathogenicity of Anti-NMDA Receptor Autoantibody From Patients With First-Episode Psychosis." 01/01/2019 - "The anti-N-methyl-D-aspartate receptor (anti-NMDAR) autoantibody is a typical synaptic protein that can bind to synaptic NMDA glutamate receptors, leading to dysfunctional glutamate neurotransmission in the brain that manifests as psychiatric symptoms (psychosis, hallucinations, and personality changes). "
4.	Toxoplasmosis 10/01/2018 - "NMDAR autoantibody seroreactivity may be a novel pathological hallmark of chronic toxoplasmosis, which raises questions about NMDAR hypofunction and neurodegeneration in the infected brain."
5.	Schizophrenia (Dementia Praecox) 01/01/2020 - "In this review, we first discuss the shared underlying mechanisms of NMDAR hypofunction in NMDAR antagonist models and the anti-NMDAR autoantibody model of schizophrenia and suggest that NMDAR hypofunction could occur in GABAergic neurons in both models. "

Related Drugs and Biologics

1.	N-Methyl-D-Aspartate Receptors (NMDA Receptors)
2.	N-Methylaspartate (NMDA)
3.	Glutamic Acid (Glutamate)
4.	Glutamate Receptors (Glutamate Receptor)
5.	Proteins (Proteins, Gene)
6.	Rituximab (Mabthera)