anti-CRMP5 autoantibody

Also Known As:

Anti-CRMP5 antibodies; Anti-CRMP5 antibody; Anti-CRMP5 autoantibodies; Anti-CV2 CRMP5 antibodies; Anti-CV2 CRMP5 antibody; Anti-CV2 antibodies; CRMP5 autoantibody; anti-collapsin-response mediator protein-5; anti-collapsin-response mediator protein-5 autoantibodies; anti-collapsin-response mediator protein-5 autoantibody

Networked: 17 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Autoantibodies: 35785
        anti-CRMP5 autoantibody: 17
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Autoantibodies: 35785
        anti-CRMP5 autoantibody: 17
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Autoantibodies: 35785
        anti-CRMP5 autoantibody: 17

Experts

1.	Cui, Li: 1 article (10/2021)
2.	Lang, Yue: 1 article (10/2021)
3.	Shao, Jie: 1 article (10/2021)
4.	Song, Jia: 1 article (10/2021)
5.	Wang, Yi-Heng: 1 article (10/2021)
6.	Zhang, Ying: 1 article (10/2021)
7.	Cohen, Devon A: 1 article (05/2021)
8.	Gaier, Eric D: 1 article (05/2021)
9.	Gise, Ryan: 1 article (05/2021)
10.	Bennett, Jeffrey L: 1 article (01/2021)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2007 - "We also have no knowledge of the existence of anti-CV2 antibodies outside of the tumor context, so that we believe that our patient probably has an occult neoplasm." 05/01/2011 - "This case widens the range of paraneoplastic manifestations of breast carcinoma to include anti-CRMP5 antibody-positive sensory ataxic demyelinating neuropathy, which, in this patient, improved after cancer treatment." 09/01/1996 - "The detection of anti-CV2 antibodies in patients with neurological disorders should be considered as an indication of the presence of an occult cancer." 05/01/2011 - "Demyelinating neuropathy with anti-CRMP5 antibodies predating diagnosis of breast carcinoma: favorable outcome after cancer therapy." 03/01/1998 - "Paraneoplastic cerebellar syndrome and optic neuritis with anti-CV2 antibodies: clinical response to excision of the primary tumor."
2.	Breast Neoplasms (Breast Cancer) 05/01/2011 - "This case widens the range of paraneoplastic manifestations of breast carcinoma to include anti-CRMP5 antibody-positive sensory ataxic demyelinating neuropathy, which, in this patient, improved after cancer treatment." 05/01/2011 - "Demyelinating neuropathy with anti-CRMP5 antibodies predating diagnosis of breast carcinoma: favorable outcome after cancer therapy."
3.	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 10/01/2005 - "Anti-CV2 antibodies are frequently associated with a paraneoplastic sensorimotor axonal neuropathy and small-cell lung cancer. " 01/01/2021 - "He was later found to have extensive stage small cell lung cancer, with further evaluation revealing seropositivity for anti-CV2 antibodies. Choreoathetosis is a known sequelae of hypoxic-ischemic brain injury, but clinicians should continue to keep an open mind. " 09/01/2014 - "Paraneoplastic chorea caused by anti-CRMP5 antibodies associated with small cell lung cancer." 08/01/2007 - "Isolated paraneoplastic optic neuropathy associated with small-cell lung cancer and anti-CV2 antibodies." 03/01/1998 - "To describe a patient with a paraneoplastic cerebellar syndrome and optic neuritis with circulating anti-CV2 antibodies and clinical improvement after excision of a small cell lung carcinoma. "
4.	Parkinsonian Disorders (Parkinsonism) 10/26/2021 - "However, Parkinsonism has not been reported as the core symptom in patients with anti-CV2 antibodies. " 03/01/2017 - "Paraneoplastic Atypical Parkinsonism with Anti-CRMP5 Antibodies and Severe Caudate and Putaminal Hypometabolism on 18-Fluorodeoxyglucose Positron Emission Tomography of the Brain." 01/01/2016 - "Severe parkinsonism associated with anti-CRMP5 antibody-positive paraneoplastic neurological syndrome and abnormal signal intensity in the bilateral basal ganglia."
5.	Chorea (Rheumatic Chorea) 01/01/2019 - "A 63-year-old man presented with insidious onset, slowly progressive generalized chorea for 1 year, later diagnosed as anti-CV2/CRMP5 autoantibody positive paraneoplastic chorea. " 09/01/2014 - "Paraneoplastic chorea caused by anti-CRMP5 antibodies associated with small cell lung cancer." 01/01/2019 - "In patients with anti-CV2/CRMP5 autoantibody-related chorea, sequential follow-up of brain magnetic resonance imaging reveals progression from active inflammation to atrophy. " 10/26/2021 - "Generally, anti-CV2 antibodies have usually been associated with cerebellar ataxia, chorea, peripheral and autonomic neuropathies, myelopathy, optic neuritis, and retinitis. "

Related Drugs and Biologics

1.	Antibodies
2.	Biomarkers (Surrogate Marker)
3.	Myelin-Oligodendrocyte Glycoprotein
4.	Immunoglobulin G (IgG)
5.	Glial Fibrillary Acidic Protein

Related Therapies and Procedures

1.	Therapeutics