N-dihydrogalactochitosan

mucoadhesive immunostimulatory polymer of beta-0-4-linked N-acetylglucosamine that is solubilized by the conjugation of galactose glycans

Also Known As:

IP 001; IP-001; IP001; N-dihydro-galacto-chitosan

Networked: 8 relevant articles (1 outcomes, 0 trials/studies)

1.	Chen, Wei R: 5 articles (01/2022 - 04/2015)
2.	Hode, Tomas: 4 articles (01/2021 - 04/2015)
3.	Lam, Samuel S K: 3 articles (01/2021 - 04/2015)
4.	Liu, Kaili: 2 articles (01/2022 - 11/2019)
5.	Korbelik, Mladen: 2 articles (01/2021 - 03/2020)
6.	Axtell, Robert C: 1 article (01/2022)
7.	DeVette, Christa I: 1 article (01/2022)
8.	Hildebrand, William H: 1 article (01/2022)
9.	Hoover, Ashley R: 1 article (01/2022)
10.	Krawic, Jason R: 1 article (01/2022)

1.	Neoplasms (Cancer) 08/01/2016 - "inCVAX is based on the induction of local immunogenic cancer cell death combined with local dendritic cell stimulation by intratumoral injection of the immune-activator N-dihydro-galacto-chitosan (GC). " 11/08/2019 - "N-Dihydrogalactochitosan Potentiates the Radiosensitivity of Liver Metastatic Tumor Cells Originated from Murine Breast Tumors." 03/01/2020 - "The biopolymer N-dihydrogalactochitosan (GC) was shown in multiple reports to act as a very effective adjunct to tumor PTT. " 11/08/2019 - "N-dihydrogalactochitosan (GC), a biocompatible immunostimulant, is known to enhance the effects of various treatment modalities in different tumor types. " 03/01/2020 - "N-dihydrogalactochitosan-supported tumor control by photothermal therapy and photothermal therapy-generated vaccine."
2.	Breast Neoplasms (Breast Cancer) 11/08/2019 - "N-Dihydrogalactochitosan Potentiates the Radiosensitivity of Liver Metastatic Tumor Cells Originated from Murine Breast Tumors." 05/03/2023 - "We applied a novel localized ablative immunotherapy (LAIT) by synergizing photothermal therapy (PTT) with intra-tumor delivering of the immunostimulant N-dihydrogalactochitosan (GC), to treat breast cancer using a mammary tumor virus-polyoma middle tumor-antigen (MMTV-PyMT) mouse model. "

1.	N-dihydrogalactochitosan
2.	Immunologic Adjuvants (Immunologic Adjuvant)
3.	Neoplasm Antigens (Tumor Antigens)
4.	Polymers
5.	Vaccines
6.	Polysaccharides (Glycans)
7.	Glucosamine (Dona)
8.	Galactose (Galactopyranose)
9.	Biopolymers (Biopolymer)
10.	Acetylglucosamine