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PDE7 inhibitor S14

Also Known As:

(4-Cyclopropyl-3,4-dihydro-2H-quinoxalin-1-yl)(4-(2,5-dichloro-phenoxy)-pyridin-3-yl)-methanone

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinazolines: 402
      - PDE7 inhibitor S14: 1

Experts

1.	Alonso-Gil, Sandra: 1 article (06/2015)
2.	Gil, Carmen: 1 article (06/2015)
3.	Martinez, Ana: 1 article (06/2015)
4.	Morales-Garcia, Jose A: 1 article (06/2015)
5.	Perez-Castillo, Ana: 1 article (06/2015)
6.	Santos, Angel: 1 article (06/2015)

Related Diseases

1.

Parkinson Disease (Parkinson's Disease)

06/01/2015 - "We have previously shown that a phosphodiesterase 7 (PDE7) inhibitor, S14, exerts potent neuroprotective and anti-inflammatory effects in different rodent models of Parkinson's disease, indicating that this compound could represent a novel therapeutic agent to stop the dopaminergic cell loss that occurs during the progression of the disease. "

Related Drugs and Biologics

1.	Type 7 Cyclic Nucleotide Phosphodiesterases