PF-06751979

Also Known As:

2-Pyridinecarboxamide, N-(2-((4aR,6S,8aR)-2-amino-4,4a,5,6-tetrahydro-6-methylpyrano(3,4-d)(1,3)thiazin-8a(8H)-yl)-4-thiazolyl)-5-(difluoromethoxy)-; N-(2-((4aR,6S,8aR)-2-Amino-6-methyl-4,4a,5,6-tetrahydropyrano(3,4-d)(1,3)thiazin-8a(8H)-yl)-1,3-thiazol-4-yl)-5-(difluoromethoxy)-2-pyridinecarboxamide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ahn, Jae Eun: 1 article (01/2019)
2.	Alexander, Robert: 1 article (01/2019)
3.	Brodney, Michael A: 1 article (01/2019)
4.	Chen, Danny: 1 article (01/2019)
5.	He, Ping: 1 article (01/2019)
6.	Leurent, Claire: 1 article (01/2019)
7.	Mancuso, Jessica: 1 article (01/2019)
8.	Margolin, Richard A: 1 article (01/2019)
9.	Qiu, Ruolun: 1 article (01/2019)
10.	Tankisheva, Ekaterina: 1 article (01/2019)

Related Diseases

1.	Alzheimer Disease (Alzheimer's Disease) 01/01/2019 - "PF-06751979 is a selective inhibitor of the beta-site amyloid precursor protein cleaving enzyme-1, which is a key aspartyl protease in the generation of amyloid-β (Aβ) peptides, thought to be critical for the cerebral degeneration observed in Alzheimer's disease. "

Related Drugs and Biologics

1.	Aspartic Acid Proteases
2.	Proteins (Proteins, Gene)
3.	Peptides (Polypeptides)
4.	Amyloid (Amyloid Fibrils)