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oxocrebanine

aporphine alkaloid from S. hainanensis

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Benzylisoquinolines: 151
    - Aporphines: 10
      - oxocrebanine: 4
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoquinolines: 34
      - Benzylisoquinolines: 151
        Aporphines: 10
        oxocrebanine: 4
  - 4 or More Rings Heterocyclic Compounds
    - Aporphines: 10
      - oxocrebanine: 4

Experts

1.	Chaichompoo, Waraluck: 1 article (08/2022)
2.	Chulrik, Wanatsanan: 1 article (08/2022)
3.	Chunglok, Warangkana: 1 article (08/2022)
4.	Chunglok, Wilanee: 1 article (08/2022)
5.	Jansakun, Chutima: 1 article (08/2022)
6.	Sattayakhom, Apsorn: 1 article (08/2022)
7.	Suksamrarn, Apichart: 1 article (08/2022)
8.	Tedasen, Aman: 1 article (08/2022)
9.	Yotmanee, Pathumwadee: 1 article (08/2022)
10.	Dong, Lin: 1 article (04/2021)

Related Diseases

1.	Acute Lung Injury 08/01/2023 - "Protective effects of Stephania pierrei tuber-derived oxocrebanine against LPS-induced acute lung injury in mice."
2.	Breast Neoplasms (Breast Cancer) 04/01/2021 - "This study aimed to assess the anti-breast cancer and Topo inhibitory activities of oxocrebanine and explore the underlying mechanisms. " 04/01/2021 - "Accordingly, oxocrebanine held a great potential for development as a novel dual Topo inhibitor for effective breast cancer treatment." 04/01/2021 - "Oxocrebanine was the anti-breast cancer active alkaloid in S. " 04/01/2021 - "Oxocrebanine: A Novel Dual Topoisomerase inhibitor, Suppressed the Proliferation of Breast Cancer Cells MCF-7 by Inducing DNA Damage and Mitotic Arrest." 04/01/2021 - "Oxocrebanine was the anti-breast cancer active aporphine alkaloid in S. "
3.	Lung Injury 08/01/2023 - "Moreover, in a murine ALI model, oxocrebanine lowers lung injury scores and lung wet/dry weight ratios while reducing inflammatory cell infiltration. "
4.	Pulmonary Edema 08/01/2023 - "Moreover, in a murine ALI model, oxocrebanine lowers lung injury scores and lung wet/dry weight ratios while reducing inflammatory cell infiltration. "
5.	Pneumonia (Pneumonitis) 08/01/2023 - "Hence, oxocrebanine might prove effective as an anti-inflammatory agent for the treatment of lung inflammation."

Related Drugs and Biologics

1.	trioctyl phosphine oxide (TOPO)
2.	Topoisomerase Inhibitors
3.	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
4.	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
5.	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)
6.	Interleukin-6 (Interleukin 6)
7.	Dinoprostone (PGE2)
8.	Proteins (Proteins, Gene)
9.	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
10.	Phosphotransferases (Kinase)