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3,10-dibromofascaplysin

Also Known As:

3,10-dibromo-13-oxo-12,13-dihydrobenzo(2,3)indolizino(8,7-b)indol-5-ium

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - Oxindoles: 118
      - 3,10-dibromofascaplysin: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        Oxindoles: 118
        3,10-dibromofascaplysin: 3
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        Oxindoles: 118
        3,10-dibromofascaplysin: 3

Experts

1.	Dyshlovoy, Sergey A: 3 articles (08/2021 - 08/2019)
2.	Amsberg, Gunhild von: 2 articles (08/2021 - 08/2019)
3.	Kaune, Moritz: 2 articles (12/2020 - 08/2019)
4.	Smirnova, Polina A: 2 articles (12/2020 - 08/2019)
5.	Zhidkov, Maxim E: 2 articles (12/2020 - 08/2019)
6.	Kantemirov, Alexey: 1 article (08/2021)
7.	Lebedev, Timofey: 1 article (08/2021)
8.	Prassolov, Vladimir: 1 article (08/2021)
9.	Shyrokova, Elena: 1 article (08/2021)
10.	Smirnova, Polina: 1 article (08/2021)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 12/01/2020 - "Efficacy and mechanism of action of marine alkaloid 3,10-dibromofascaplysin (DBF) were investigated in human prostate cancer (PCa) cells harboring different levels of drug resistance. " 12/01/2020 - "Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells." 08/25/2019 - "3,10-Dibromofascaplysin was able to target metabolic activity of the prostate cancer cells, without disrupting cell membrane's integrity and had a wide therapeutic window amongst the fascaplysin alkaloids."
2.	Myeloid Leukemia (Leukemia, Myelocytic) 08/27/2021 - "Here, we studied the effect of the recently synthesized marine alkaloid 3,10-dibromofascaplysin (DBF) in myeloid leukemia cells. "
3.	Leukemia 08/27/2021 - "Cytotoxic Marine Alkaloid 3,10-Dibromofascaplysin Induces Apoptosis and Synergizes with Cytarabine Resulting in Leukemia Cell Death."

Related Drugs and Biologics

1.	Alkaloids
2.	Cytarabine (Cytosar-U)
3.	fascaplysine