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ureido-N-hexyl deoxynojirimycin

endoplasmic reticulum alpha-glucosidases I and II inhibitor

Also Known As:

IHVR 19029; IHVR-19029; ureido-N-hexyl DNJ; ureido-N-hexyl deoxynojirimycine

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Block, Timothy M: 2 articles (01/2018 - 02/2017)
2.	Chang, Jinhong: 2 articles (01/2018 - 02/2017)
3.	Du, Yanming: 2 articles (01/2018 - 02/2017)
4.	Guo, Fang: 2 articles (01/2018 - 02/2017)
5.	Guo, Jia: 2 articles (01/2018 - 02/2017)
6.	Guo, Ju-Tao: 2 articles (01/2018 - 02/2017)
7.	Lu, Huagang: 2 articles (01/2018 - 02/2017)
8.	Ma, Julia: 2 articles (01/2018 - 02/2017)
9.	Su, Qing: 2 articles (01/2018 - 02/2017)
10.	Wu, Shuo: 2 articles (01/2018 - 02/2017)

Related Diseases

1.	Ebola Hemorrhagic Fever 01/01/2018 - "Moreover, in a mouse model of Ebola virus infection, combination of sub-optimal doses of IHVR-19029 and T-705 significantly increased the survival rate of infected animals. "
2.	Yellow Fever 01/01/2018 - "Indeed, combination of IHVR-19029 and T-705 synergistically inhibited the replication of Yellow fever and Ebola viruses in cultured cells. "
3.	Marburg Virus Disease 02/09/2017 - "IHVR-19029 (6) is a lead endoplasmic reticulum α-glucosidases I and II inhibitor, which efficiently protected mice from lethal Ebola and Marburg virus infections via injection route, but suffered from low bioavailability and off-target interactions with gut glucosidases when administered orally. "
4.	Fever (Fevers) 01/01/2018 - "Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo."

Related Drugs and Biologics

1.	Glucosidases
2.	Antiviral Agents (Antivirals)