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OR-2100

Demethylating agent

Also Known As:

6-Methoxy-2-methyl-3-pyridinamine hydrochloride (1:1)

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - OR-2100: 2

Experts

1.	Ushijima, Toshikazu: 2 articles (01/2022 - 01/2019)
2.	Fukuda-Kurahashi, Yuki: 1 article (01/2022)
3.	Hayashi, Yoshihiro: 1 article (01/2022)
4.	Hirai, Hideyo: 1 article (01/2022)
5.	Kamachi, Kazuharu: 1 article (01/2022)
6.	Kimura, Shinya: 1 article (01/2022)
7.	Kurahashi, Yuki: 1 article (01/2022)
8.	Okada, Seiji: 1 article (01/2022)
9.	Ureshino, Hiroshi: 1 article (01/2022)
10.	Watanabe, Tatsuro: 1 article (01/2022)

Related Diseases

1.	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/01/2022 - "Targeting DNMT1 by demethylating agent OR-2100 increases tyrosine kinase inhibitors-sensitivity and depletes leukemic stem cells in chronic myeloid leukemia."
2.	Neoplasms (Cancer) 01/01/2019 - "The anti-tumor effect and DNA demethylation effect of OR-2003 and OR-2100 were comparable to that of DAC with fewer adverse effects in vivo. "

Related Drugs and Biologics

1.	Tyrosine Kinase Inhibitors