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SAB-185

human IgG polyclonal antibody derived from plasma of transchromosomal (Tc) bovine targeted to the spike protein of SARS COV-2

Also Known As:

SAB 185; immunoglobulin Tc-hIgG-SARS-CoV-2

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Klimstra, William B: 2 articles (01/2022 - 07/2021)
2.	Wu, Hua: 2 articles (01/2022 - 07/2021)
3.	Bausch, Christoph L: 1 article (01/2022)
4.	Dunn, Matthew D: 1 article (01/2022)
5.	Egland, Kristi A: 1 article (01/2022)
6.	Gilliland, Theron C: 1 article (01/2022)
7.	Liu, Zhuoming: 1 article (01/2022)
8.	Luke, Thomas C: 1 article (01/2022)
9.	Sullivan, Eddie J: 1 article (01/2022)
10.	Whelan, Sean P J: 1 article (01/2022)

Related Diseases

1.	Vesicular Stomatitis 01/01/2022 - "The resulting Tc-hIgG-SARS-CoV-2, termed SAB-185, efficiently neutralizes SARS-CoV-2, and vesicular stomatitis virus (VSV) SARS-CoV-2 chimeras in vitro. "
2.	Infections 07/26/2021 - "In the hamster model, prophylactic SAB-185 treatment protected the hamsters from fatal disease and minimized clinical signs of infection. "
3.	COVID-19 07/14/2023 - "SAB-185 was safe and generally well tolerated and demonstrated modest antiviral activity in predominantly low-risk nonhospitalized adults with COVID-19. " 07/14/2023 - "Phase 2 Safety and Antiviral Activity of SAB-185, a Novel Polyclonal Antibody Therapy for Nonhospitalized Adults With COVID-19." 07/14/2023 - "SAB-185, a novel fully human IgG polyclonal immunoglobulin product, underwent phase 2 evaluation for nonhospitalized adults with mild-moderate coronavirus disease 2019 (COVID-19). "

Related Drugs and Biologics

1.	Immunoglobulins (Immunoglobulin)
2.	Immunoglobulin G (IgG)
3.	Antiviral Agents (Antivirals)

Related Therapies and Procedures

1.	Therapeutics