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IRL201104

peptide derived from the endogenous immuno-regulatory protein (mTB chaperonin 60.1)

Also Known As:

IRL 1104; IRL 201104; IRL-1104; IRL-201104

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Molecular Chaperones: 1279
    - Heat-Shock Proteins: 8088
      - Chaperonins: 222
        IRL201104: 2
- Peptides: 82426
  - Peptide Fragments: 373
    - IRL201104: 2
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Acid Anhydride Hydrolases
      - Adenosine Triphosphatases: 8623
        Chaperonins: 222
        IRL201104: 2

Experts

1.	E-Lacerda, Rodrigo R: 2 articles (11/2021 - 01/2020)
2.	Kanabar, Varsha: 2 articles (11/2021 - 01/2020)
3.	Man, Francis: 2 articles (11/2021 - 01/2020)
4.	Page, Clive P: 2 articles (11/2021 - 01/2020)
5.	Riffo-Vasquez, Yanira: 2 articles (11/2021 - 01/2020)
6.	Federici Canova, Donata: 1 article (11/2021)
7.	Gomes Ferreira, Sueli: 1 article (11/2021)
8.	Nadkarni, Suchita: 1 article (11/2021)
9.	Perretti, Mauro: 1 article (11/2021)
10.	Coates, Anthony R M: 1 article (01/2020)

Related Diseases

1.	Pneumonia (Pneumonitis) 11/01/2021 - "To further investigate the anti-inflammatory properties of Cpn60.1 and IRL201104, we have investigated these molecules in a model of nonallergic lung inflammation. " 01/01/2020 - "In the present study, we have investigated the effect of a shorter peptide sequence derived from Cpn 60.1, named IRL201104, on allergic lung inflammation induced by ovalbumin (OVA) in mice and by house dust mite (HDM) in guinea pigs, as well as investigating the action of IRL201104 on human cells in vitro. " 11/01/2021 - "A peptide derived from chaperonin 60.1, IRL201104, inhibits LPS-induced acute lung inflammation."
2.	Inflammation (Inflammations) 11/01/2021 - "Chaperonin 60.1 (Cpn60.1) is a protein derived from Mycobacterium tuberculosis that has been shown, along with its peptide fragment IRL201104, to have beneficial effects in models of allergic inflammation. "
3.	Eosinophilia 01/01/2020 - "The protective effect of intranasal IRL201104 against OVA-induced eosinophilia persisted for up to 20 days post-treatment. "
4.	Asthma (Bronchial Asthma) 01/01/2020 - "Our results also show that A20 expression was significantly reduced in blood leucocytes and ASM obtained from patients with asthma compared to cells obtained from healthy subjects which were restored after incubation with IRL201104 in vitro, when added alone, or in combination with LPS or TNF-α in ASM. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Ovalbumin
3.	Chaperonins
4.	Proteins (Proteins, Gene)
5.	Peptide Fragments