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IRW peptide

Angiotensin Converting Enzyme 2 (ACE2) activating peptide

Also Known As:

Ile-Arg-Trp

Networked: 7 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - IRW peptide: 7

Experts

1.	Wu, Jianping: 3 articles (04/2022 - 10/2016)
2.	Liao, Wang: 2 articles (05/2018 - 10/2016)
3.	Jiang, Xu: 1 article (04/2022)
4.	Fan, Hongbing: 1 article (05/2018)
5.	Ding, Sujuan: 1 article (01/2018)
6.	Fang, Jun: 1 article (01/2018)
7.	Jiang, Hongmei: 1 article (01/2018)
8.	Liu, Gang: 1 article (01/2018)
9.	Ma, Yong: 1 article (01/2018)
10.	Wang, Hua: 1 article (01/2018)

Related Diseases

1.	Insulin Resistance 04/04/2022 - "Egg white protein ovotransferrin derived peptide IRW (Ile-Arg-Trp) was found to improve tumor necrosis factor alpha (TNF-α) or angiotensin II induced insulin resistance in L6 cells. "
2.	Colitis 02/14/2023 - "Our study investigated the association between Ile-Arg-Trp (IRW), a dietary oligopeptide, and intestinal microbial changes during the relief of colitis using different concentrations of IRW. " 01/01/2018 - "In this study, a colitis model induced by dextran sodium sulfate (DSS) in mice is used to evaluate whether the presence of bioactive peptides IRW (Ile-Arg-Trp) and IQW (Ile-Gln-Trp) peptides is advantageous. "
3.	Inflammation (Inflammations) 11/09/2022 - "Egg White Protein Ovotransferrin-Derived IRW (Ile-Arg-Trp) Inhibits LPS-Induced Barrier Integrity Dysfunction and Inflammation in Caco-2 Cells." 10/05/2016 - "Egg white ovotransferrin-derived tripeptide IRW (Ile-Arg-Trp) was previously shown to exert antihypertensive effect by reducing Ang II synthesis as well as endothelial cell inflammation and endothelial dysfunction. "
4.	Osteoporosis 01/01/2022 - "Tripeptide IRW (Ile-Arg-Trp) as a Potential Nutraceutical Intervention in Osteoporosis."
5.	Hypertension (High Blood Pressure) 05/23/2018 - "In addition to reducing high blood pressure in spontaneously hypertensive rats, egg white ovotransferrin-derived antihypertensive IRW (Ile-Arg-Trp) was shown to exert antiproliferative, antioxidant, and anti-inflammatory effects in A7r5 cells (a vascular smooth muscle cell line) against Ang II stimulation, further indicating its potential in retarding vascular remodelling. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Conalbumin
3.	Egg Proteins
4.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
5.	Angiotensin II
6.	Oligopeptides
7.	Dextrans (Dextran)
8.	sodium sulfate (sodium bisulfate)
9.	Antihypertensive Agents (Antihypertensives)
10.	Antioxidants