demethylcurcumin

Also Known As:

(1E,6E)-1-(3,4-dihydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione; monodemethylcurcumin

Networked: 5 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Diarylheptanoids: 471
        Curcumin: 10678
        demethylcurcumin: 5
      - Benzene Derivatives: 17
        Phenols: 677
        Catechols: 121
        Curcumin: 10678
        demethylcurcumin: 5
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Heptanes: 70
        Diarylheptanoids: 471
        Curcumin: 10678
        demethylcurcumin: 5

Experts

1.	Han, Chuan-Hsiao: 3 articles (03/2020 - 06/2019)
2.	Hou, Wen-Chi: 3 articles (03/2020 - 06/2019)
3.	Lee, Tai-Lin: 3 articles (03/2020 - 06/2019)
4.	Liu, Yuh-Hwa: 3 articles (03/2020 - 06/2019)
5.	Lee, Yi-Shan: 2 articles (01/2020 - 06/2019)
6.	Changtam, Chatchawan: 2 articles (01/2016 - 01/2015)
7.	Pinkaew, Decha: 2 articles (01/2016 - 01/2015)
8.	Suksamrarn, Apichart: 2 articles (01/2016 - 01/2015)
9.	Tocharus, Chainarong: 2 articles (01/2016 - 01/2015)
10.	Tocharus, Jiraporn: 2 articles (01/2016 - 01/2015)

Related Diseases

1.	Neuroblastoma 01/01/2015 - "Pretreatment with di-O-demethylcurcumin for 2 h, which was followed by Aβ25-35 (10 µM) in human neuroblastoma SK-N-SH cells improved cell viability by using MTS assay and decreased neuronal cell apoptosis. " 01/01/2016 - "The present study aimed to evaluate the potential involvement of di-O-demethylcurcumin, an analog of curcuminoid, on Aβ-induced neurotoxicity in culture neuroblastoma cells (SK-N-SH cells) through the activation of nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and the suppression of nuclear factor-κB (NF-κB) signaling pathway and their downstream targets. "
2.	Amnesia (Dissociative Amnesia) 03/01/2020 - "Acetylcholinesterase inhibitory activity and neuroprotection in vitro, molecular docking, and improved learning and memory functions of demethylcurcumin in scopolamine-induced amnesia ICR mice."
3.	Hemolysis 01/01/2020 - "Correction to: Anti-glycation, anti-hemolysis, and ORAC activities of demethylcurcumin and tetrahydroxycurcumin in vitro and reductions of oxidative stress in D-galactose-induced BALB/c mice in vivo." 06/27/2019 - "The demethylcurcumin and tetrahydroxycurcumin exhibited anti-glycation, anti-hemolysis, and ORAC activities, and showed much better and significant difference (P < 0.05) compared to those of curcumin in vitro. " 06/27/2019 - "Anti-glycation, anti-hemolysis, and ORAC activities of demethylcurcumin and tetrahydroxycurcumin in vitro and reductions of oxidative stress in D-galactose-induced BALB/c mice in vivo." 06/27/2019 - "The bovine serum albumin/galactose of non-enzymatic glycation models, radical-induced hemolysis, and oxygen radical absorbance capacity (ORAC) were studied in vitro, and the D-galactose-induced oxidative stress in BALB/c mice and then demethylcurcumin or tetrahydroxycurcumin interventions in vivo. "

Related Drugs and Biologics

1.	Scopolamine (Hyoscine)
2.	Acetylcholinesterase
3.	Diarylheptanoids
4.	Galactose (Galactopyranose)
5.	Reactive Oxygen Species (Oxygen Radicals)
6.	Bovine Serum Albumin
7.	Curcumin