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NUCC-390

agonist of the CXCR4 Receptor

Also Known As:

piperidin-1-yl(1-propyl-5-((2-(pyridin-4-yl)ethyl)amino)-4,5,6,7-tetrahydro-1H-indazol-3-yl)methanone

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indazoles: 179
      - NUCC-390: 2

Experts

1.	D'Este, Giorgia: 1 article (01/2020)
2.	Lista, Florigio: 1 article (01/2020)
3.	Mattarei, Andrea: 1 article (01/2020)
4.	Megighian, Aram: 1 article (01/2020)
5.	Montecucco, Cesare: 1 article (01/2020)
6.	Negro, Samuele: 1 article (01/2020)
7.	Rigoni, Michela: 1 article (01/2020)
8.	Stazi, Marco: 1 article (01/2020)

Related Diseases

1.	Snake Bites (Snake Bite) 01/01/2020 - "NUCC-390 could become an additional treatment, common to many snake envenomings, that can be delivered after the bite to reduce death by respiratory deficits and to shorten and improve functional recovery." 03/13/2023 - "These findings qualify NUCC-390 as a promising novel therapeutics capable of improving the recovery from the paralysis caused by the snakebite of the two neurotoxic Alpine vipers."
2.	Paralysis (Palsy) 03/13/2023 - "These findings qualify NUCC-390 as a promising novel therapeutics capable of improving the recovery from the paralysis caused by the snakebite of the two neurotoxic Alpine vipers." 01/01/2020 - "Using imaging of the neuromuscular junction and electrophysiological analysis, we found that NUCC-390 administration after injection of either the purified neuroparalytic Taipoxin or the whole Taipan venom, significantly accelerates the recovery from paralysis. "
3.	Bites and Stings (Sting) 01/01/2020 - "NUCC-390 could become an additional treatment, common to many snake envenomings, that can be delivered after the bite to reduce death by respiratory deficits and to shorten and improve functional recovery."

Related Drugs and Biologics

1.	Venoms
2.	taipoxin

Related Therapies and Procedures

1.	Therapeutics