11-methoxytabersonine

aspidosperma-type alkaloid isolated from Tabernaemontana bovina; has anti-neoplastic properties

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2022 - "Anti-leukemic effect and molecular mechanism of 11-methoxytabersonine from Melodinus cochinchinensis via network pharmacology, ROS-mediated mitochondrial dysfunction and PI3K/Akt signaling pathway."
2.	Lung Neoplasms (Lung Cancer) 01/01/2020 - "11-Methoxytabersonine Induces Necroptosis with Autophagy through AMPK/mTOR and JNK Pathways in Human Lung Cancer Cells." 01/01/2020 - "In the current project, 11-methoxytabersonine (11-MT), an aspidosperma-type alkaloid isolated from Tabernaemontana bovina, significantly inhibited the viability of two human lung cancer cell lines A549 and H157, and the molecular mechanisms were thus investigated. "

1.	Alkaloids