SARS-CoV N protein

Also Known As:

N protein, SARS-CoV; N protein, SARS virus; N protein, Severe acute respiratory syndrome virus; nucleocapsid protein, SARS-CoV; nucleocapsid protein, Severe Acute Respiratory Syndrome Coronavirus

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Viral Proteins: 4250
    - Viral Structural Proteins: 171
      - Nucleocapsid Proteins: 749
        Coronavirus Nucleocapsid Proteins: 8
        SARS-CoV N protein: 11

Experts

1.	Timani, Khalid Amine: 2 articles (01/2006 - 09/2005)
2.	Chen, Chiung-Yao: 1 article (04/2012)
3.	Juang, Yue-Li: 1 article (04/2012)
4.	Lee, Shen-Kao: 1 article (04/2012)
5.	Li, Hui-Chun: 1 article (04/2012)
6.	Lo, Shih-Yen: 1 article (04/2012)
7.	Ma, Hsin-Chieh: 1 article (04/2012)
8.	Wang, Chia-Wen: 1 article (04/2012)
9.	Wei, Wei-Yen: 1 article (04/2012)
10.	Yang, Chee-Hing: 1 article (04/2012)

Related Diseases

1.	Infections 07/01/2008 - "Proliferation of human peripheral blood lymphocytes and other human cell lines was significantly inhibited by the infection of recombinant retrovirus expressing SARS-CoV N protein." 12/01/2007 - "Thus, this investigation provided the preliminary data to determine the phosphorylation sites in the SARS-CoV N protein, and partially clarified the argument regarding the phosphorylation possibility of the N protein during the infection process of SARS-CoV to human host." 12/01/2006 - "Severe acute respiratory syndrome-coronavirus nucleocapsid (SARS-CoV N) protein has been found to be important to the processes related to viral pathogenesis, such as virus replication, interference of the cell process and modulation of host immune response; detection of the antigen has been used for the early diagnosis of infection. " 09/01/2005 - "Our results showed that the SARS-CoV N protein can significantly activate NF-kappaB only in Vero E6 cells, which are susceptible to SARS-CoV infection, but not in Vero or HeLa cells. " 07/01/2004 - "Antibodies against SARS-CoV N protein appear at the early stage of infection, therefore, N protein-based ELISA could serve as a simple, sensitive, and specific test for diagnosing SARS-CoV infection."
2.	Severe Acute Respiratory Syndrome 04/01/2005 - "To develop a method for quantitative detection of severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) N protein by timed-resolved fluoroimmunoassay (TRFIA). " 01/20/2007 - "In addition, we have shown that purified severe acute respiratory syndrome (SARS)-CoV N protein also has RNA chaperone activity. "
3.	Porcine Reproductive and Respiratory Syndrome (PRRS) 02/01/2011 - "These results indicate that SARS-CoV N protein targets the initial step, probably the cellular PRRs (pattern recognition receptors)-RNAs-recognition step in the innate immune pathways, to suppress IFN expression responses. "
4.	Thrombosis (Thrombus) 09/01/2009 - "Taken together, our findings did not support the model in which SARS-CoV N protein specifically modulates transcription of the FGL2 gene to cause fibrosis and vascular thrombosis."
5.	Liver Diseases (Liver Disease) 04/01/2012 - "It is reasonable to assume that an inhibition of PKL activity due to interaction with SARS-CoV N protein is likely to cause the death of the hepatocytes, which results in the elevation of serum alanine aminotransferase and liver dysfunction noted in most SARS patients. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Pattern Recognition Receptors
3.	NF-kappa B (NF-kB)
4.	RNA (Ribonucleic Acid)
5.	Antigens
6.	Antibodies
7.	Alanine Transaminase (SGPT)