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5,6,7,8-tetrahydro-1,6-naphthyridine

scaffold for allosteric HIV-1 integrase inhibitor synthesis

Also Known As:

tetrahydro-1,6-naphthyridine

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Naphthyridines: 2
      - 5,6,7,8-tetrahydro-1,6-naphthyridine: 1

Experts

1.	Allard, Christopher W: 1 article (01/2019)
2.	Cianci, Christopher: 1 article (01/2019)
3.	Connolly, Timothy: 1 article (01/2019)
4.	Jenkins, Susan: 1 article (01/2019)
5.	Johnson, Barry L: 1 article (01/2019)
6.	Kish, Kevin: 1 article (01/2019)
7.	Krystal, Mark: 1 article (01/2019)
8.	Lewis, Hal A: 1 article (01/2019)
9.	Li, Chen: 1 article (01/2019)
10.	McAuliffe, Brian: 1 article (01/2019)

Related Diseases

1.	Infections 01/01/2019 - "A series of 5,6,7,8-tetrahydro-1,6-naphthyridine derivatives targeting the allosteric lens-epithelium-derived-growth-factor-p75 (LEDGF/p75)-binding site on HIV-1 integrase, an attractive target for antiviral chemotherapy, was prepared and screened for activity against HIV-1 infection in cell culture. "

Related Drugs and Biologics

1.	Antiviral Agents (Antivirals)
2.	Human immunodeficiency virus 1 p31 integrase protein
3.	lens epithelium-derived growth factor

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)