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human ACE2 protein

RefSeq NM_001371415

Also Known As:

ACE2 protein, human; ACEH protein, human; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, human; angiotensin converting enzyme 2, human

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Exopeptidases: 68
        Carboxypeptidases: 268
        Angiotensin-Converting Enzyme 2: 2143
        human ACE2 protein: 6

Experts

1.	Ferguson, Ian D: 1 article (02/2021)
2.	Khavari, Paul A: 1 article (02/2021)
3.	Miao, Weili: 1 article (02/2021)
4.	Ramanathan, Muthukumar: 1 article (02/2021)
5.	Chen, Tien-Hao: 1 article (01/2021)
6.	Fomenkov, Alexey: 1 article (01/2021)
7.	Xu, Shuang-Yong: 1 article (01/2021)
8.	Yigit, Erbay: 1 article (01/2021)
9.	Li, Jianping: 1 article (03/2020)
10.	Liu, Mengyuan: 1 article (03/2020)

Related Diseases

1.	Infections 10/25/2023 - "During infection, the spike protein of SARS-CoV-2 interacts with the human ACE2 protein via its receptor binding domain (RBD), and it is known that engineered forms of ACE2 can compete with wild-type (WT) ACE2 for binding to inhibit infection. " 02/22/2021 - "In particular, the focus is on mutations of Spike protein, which binds human ACE2 protein enabling SARS-CoV2 entry and infection. " 01/01/2021 - "The SARS-CoV-2 viral genome contains a positive-strand single-stranded RNA of ∼30 kb. Human ACE2 protein is the receptor for SARS-CoV-2 virus attachment and infection. "
2.	Virus Diseases (Viral Diseases) 03/01/2020 - "As interaction of COVID-19 virus spike and ACE2 is essential for virus infection, COVID-19-specific vaccine based on spike protein, small molecule compound interrupting their interaction, human monoclonal antibody based on receptor-binding domain, and recombinant human ACE2 protein (rhuACE2) have aroused the interests of researchers. "
3.	Cardiovascular Diseases (Cardiovascular Disease) 01/01/2013 - "Recombinant soluble human ACE2 protein has been demonstrated to exhibit beneficial effects in various animal models, including cardiovascular diseases. "
4.	COVID-19 10/01/2023 - "Biologically, protein-protein interactions between SARS-CoV-2 surface spike (S) protein and human ACE2 protein are the key mechanism behind the COVID-19 disease. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Vaccines
3.	RNA (Ribonucleic Acid)
4.	Monoclonal Antibodies