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osocimab

a long-acting, fully human monoclonal antibody that inhibits factor XIa

Also Known As:

BAY 1213790; BAY-1213790; BAY1213790

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Cave, Brandon E: 1 article (03/2021)
2.	Shah, Samarth P: 1 article (03/2021)
3.	Beavers, Craig J: 1 article (12/2020)
4.	Wayne, Nathaniel B: 1 article (12/2020)
5.	Bauersachs, Rupert: 1 article (01/2020)
6.	Becker, Bastian: 1 article (01/2020)
7.	Berkowitz, Scott D: 1 article (01/2020)
8.	Freitas, Maria C S: 1 article (01/2020)
9.	Lassen, Michael R: 1 article (01/2020)
10.	Metzig, Carola: 1 article (01/2020)

Related Diseases

1.	Venous Thromboembolism 12/01/2020 - "Osocimab: A Novel Agent in Preventing Venous Thromboembolism." 01/01/2020 - "Effect of Osocimab in Preventing Venous Thromboembolism Among Patients Undergoing Knee Arthroplasty: The FOXTROT Randomized Clinical Trial." 01/01/2020 - "Among patients undergoing knee arthroplasty, postoperative osocimab 0.6 mg/kg, 1.2 mg/kg, and 1.8 mg/kg met criteria for noninferiority compared with enoxaparin, and the preoperative 1.8-mg/kg dose of osocimab met criteria for superiority compared with enoxaparin for the primary outcome of incidence of venous thromboembolism at 10 to 13 days postoperatively. "
2.	Hemorrhage 03/01/2021 - "Both osocimab and IONIS-FXI have been evaluated in patients undergoing orthopedic surgery and demonstrated superiority to enoxaparin without increasing major bleeding. " 01/01/2020 - "Major or clinically relevant nonmajor bleeding was observed in up to 4.7% of those receiving osocimab, 5.9% receiving enoxaparin, and 2% receiving apixaban. "

Related Drugs and Biologics

1.	Enoxaparin (Lovenox)
2.	Dihydrotachysterol (AT 10)
3.	apixaban

Related Therapies and Procedures

1.	Knee Replacement Arthroplasty (Total Knee Replacement)
2.	Orthopedic Procedures