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NC009-1 compound

indole compound; exact structure unknown

Also Known As:

NC009-1

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - NC009-1 compound: 3

Experts

1.	Chang, Kuo-Hsuan: 1 article (01/2019)
2.	Chen, Chiung-Mei: 1 article (01/2019)
3.	Chen, Yi-Chun: 1 article (01/2019)
4.	Chiu, Ya-Jen: 1 article (01/2019)
5.	Hsu, Wen-Chuin: 1 article (01/2019)
6.	Huang, Chen-Hsiang: 1 article (01/2019)
7.	Huang, Hei-Jen: 1 article (01/2019)
8.	Lee-Chen, Guey-Jen: 1 article (01/2019)
9.	Lin, Chia-Wei: 1 article (01/2019)
10.	Lin, Chih-Hsin: 1 article (01/2019)

Related Diseases

1.	Neuroinflammatory Diseases 01/30/2023 - "These results strengthen the involvement of neuroinflammation and oxidative stress in PD pathogenic mechanism, and indicate NC009-1 as a potential drug candidate for PD treatment." 11/01/2023 - "In BE(2)-M17 cells expressing A53T α-synuclein aggregates, LM-021 and NC009-1 reduced α-synuclein aggregation, neuroinflammation, oxidative stress and apoptosis, and promoted neurite outgrowth. " 01/30/2023 - "Using 1-methyl-4-phenylpyridinium (MPP+)-activated human microglial HMC3 cells and the sub-chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model of PD, we found the potential of indole derivative NC009-1 against neuroinflammation, oxidative stress, and neurodegeneration for PD. "
2.	Inflammation (Inflammations) 11/01/2023 - "Coumarin-chalcone hybrid LM-021 and indole derivative NC009-1 targeting inflammation and oxidative stress to protect BE(2)-M17 cells against α-synuclein toxicity."
3.	Alzheimer Disease (Alzheimer's Disease) 01/01/2019 - "Indole Compound NC009-1 Augments APOE and TRKA in Alzheimer's Disease Cell and Mouse Models for Neuroprotection and Cognitive Improvement."

Related Drugs and Biologics

1.	indole
2.	Synucleins
3.	1-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)
4.	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)
5.	Chalcone (Benzalacetophenone)
6.	Apolipoproteins E (ApoE)
7.	coumarin