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xylopic acid

Crystalline diterpene that belongs to the class of kauranes

Also Known As:

15-acetoxykaur-16-en-18-oic acid

Networked: 14 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - Kaurane Diterpenes: 93
        xylopic acid: 14

Experts

1.	Ameyaw, Elvis Ofori: 4 articles (06/2022 - 09/2015)
2.	Boakye-Gyasi, Eric: 4 articles (12/2016 - 10/2012)
3.	Woode, Eric: 4 articles (12/2016 - 10/2012)
4.	Biney, Robert Peter: 3 articles (06/2022 - 12/2016)
5.	Osafo, Newman: 3 articles (01/2022 - 11/2018)
6.	Antwi, Aaron O: 2 articles (01/2022 - 11/2018)
7.	Abotsi, Wonder Kofi Mensah: 2 articles (12/2016 - 09/2015)
8.	Abotsi, Wonder K M: 2 articles (04/2014 - 10/2012)
9.	Ameyaw, Elvis O: 2 articles (04/2014 - 10/2012)
10.	Amoateng, Patrick: 1 article (06/2022)

Related Diseases

1.	Malaria 02/25/2021 - "Xylopic acid-amodiaquine and xylopic acid-artesunate combinations are effective in managing malaria in Plasmodium berghei-infected mice."
2.	Neuralgia (Stump Neuralgia) 04/01/2014 - "Anti-allodynic and Anti-hyperalgesic effects of an ethanolic extract and xylopic acid from the fruits of Xylopia aethiopica in murine models of neuropathic pain." 08/01/2019 - "Xylopic acid (XA) has been reported to exhibit analgesic activity, alleviate neuropathic pain in rodents, and demonstrate anti-inflammatory effects. " 04/01/2014 - "An animal model of vincristine-induced sensory neuropathy was developed after repeated intraperitoneal injection in rats and used in the present work to study the effects of the ethanolic extract of X. aethiopica (XAE) and its diterpene xylopic acid (XA) in vincristine-induced neuropathic pain. "
3.	Neoplasms (Cancer) 10/01/2009 - "This study evaluated the potential cytotoxicity of the natural diterpenoids kauren-19-oic acid (KA), 14-hydroxy-kaurane (1) and xylopic acid (2), and semi-synthetic derivatives of KA (3-5) towards human cancer cell lines (K562, HL60, MDA-MB435 and SF295) and lymphocytes. " 06/01/2022 - "Institute of Cancer Research (ICR) mice received oral doses of the extract of Xylopia aethiopica (XAE; 30, 100 and 300 mg/kg), xylopic acid (XA; 30, 100 and mg/kg), citicoline (300 mg/kg), piracetam (300 mg/kg) or ketamine (30 mg/kg) and saline (vehicle). "
4.	Inflammation (Inflammations) 11/27/2018 - "Conclusion This study establishes that xylopic acid has anti-inflammatory action in acute inflammation."
5.	Pain (Aches) 09/01/2015 - "Fruit extracts of Xylopia aethiopica are used traditionally in the management of pain disorders and xylopic acid (XA) present in the fruit extract have been shown to possess analgesic properties in animals. " 10/01/2012 - "Little pharmacological data exists in scientific literature of the effect of the fruit extract and its major diterpene, xylopic acid, on pain. "

Related Drugs and Biologics

1.	Amodiaquine (Camoquin)
2.	Artesunate
3.	Diterpenes
4.	Vincristine (Oncovin)
5.	Acids
6.	Analgesics (Analgesic Drugs)
7.	Acetic Acid (Vinegar)
8.	Interleukin-6 (Interleukin 6)
9.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
10.	Piracetam (Nootropil)

Related Therapies and Procedures

1.	Intraperitoneal Injections