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VU0486846

M1 (muscarinic acetylcholine receptor subtype 1) positive allosteric modulator

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - VU0486846: 1
  - Oxazines: 9
    - Morpholines: 6
      - VU0486846: 1

Related Diseases

1.

Neuroinflammatory Diseases

11/15/2022 - "Chronic enhancement of the activity of the M1 receptor with the positive allosteric modulator (PAM) VU0486846 reduced the abundance of prion-induced molecular markers of neuroinflammation and mitochondrial dysregulation in the hippocampus and normalized the abundance of those associated with neurotransmission, including synaptic and postsynaptic signaling components. "

Related Drugs and Biologics

1.	Prions