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S007-867

synthetic inhibitor of collagen induced platelet activation

Also Known As:

tertbutyl ((S)-1-(4-methyl-benyl)-5-oxopyrrolidine-2-carbonyl) piperidin-3-yl) methylcarbamate

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - S007-867: 2
  - Piperidines: 17
    - S007-867: 2

Experts

1.	Aggarwal, Hobby: 1 article (01/2018)
2.	Barthwal, Manoj Kumar: 1 article (01/2018)
3.	Bihan, Dominique: 1 article (01/2018)
4.	Dhankani, Priyanka: 1 article (01/2018)
5.	Dikshit, Dinesh Kumar: 1 article (01/2018)
6.	Dikshit, Madhu: 1 article (01/2018)
7.	Farndale, Richard W: 1 article (01/2018)
8.	Kumar, Sachin: 1 article (01/2018)
9.	Misra, Ankita: 1 article (01/2018)
10.	Pandey, Chandra Prakash: 1 article (01/2018)

Related Diseases

1.	Thrombosis (Thrombus) 01/01/2018 - "In mice, following ferric chloride induced thrombosis in either carotid or mesenteric artery; S007-867 significantly prolonged the vessel occlusion time (1.2-fold) and maintained a sustained blood flow velocity for >30 min. " 01/01/2018 - "Moreover, when blood was perfused over a highly thrombogenic combination of collagen mimicking peptides like CRP-GFOGER-VWF-III, S007-867 significantly reduced total thrombus volume or ZV50 (53.4 ± 5.7%). " 01/01/2018 - "Aspirin, clopidogrel, and S007-867 significantly reduced thrombus weight in arterio-venous (AV) shunt model in rats. "
2.	Hemorrhage 07/01/2016 - "S007-867 is a promising novel antiplatelet agent with better efficacy and lesser bleeding risk than existing agents. "

Related Drugs and Biologics

1.	Platelet Aggregation Inhibitors (Antiplatelet Drugs)
2.	Peptides (Polypeptides)
3.	Collagen
4.	Aspirin (Acetylsalicylic Acid)
5.	Clopidogrel (Plavix)
6.	ferric chloride