ceragenins

01/01/2020 - "Development of ceragenins should be viewed as one of the valid strategies to provide new treatment options against infections associated with CPE. "
08/24/2023 - "Ceragenins (CSAs) that mimic the activities of antimicrobial peptides may be new options for the treatment of infections caused by multidrug-resistant pathogens. "
05/26/2022 - "Moreover, with some strains, the synergy of ceragenins with conventional antibiotics was observed Conclusion: Our data suggest that ceragenins are promising agents for future development of new methods for treatment of infections caused by S. "
08/27/2019 - "These results suggest that ceragenins may play a role in treating infections that are resistant to known antibiotics."
04/01/2019 - "These results suggest the potential use of ceragenins in treating VVC, including infections caused by fluconazole-resistant isolates."

01/01/2023 - "Ceragenins exhibit bactericidal properties that are independent of the ionic strength in the environment mimicking cystic fibrosis sputum."
07/01/2021 - "Antibacterial and antibiofilm activities of ceragenins against Achromobacter species isolated from cystic fibrosis patients."
03/07/2018 - "These features of ceragenins make them attractive potential therapeutics for persistent infections in the lung, including those associated with cystic fibrosis. "
01/01/2023 - "The purpose of the work was to investigate the impact of sodium chloride (NaCl) on the antimicrobial efficacy of ceragenins (CSAs) and antimicrobial peptides (AMPs) against bacterial and fungal pathogens associated with cystic fibrosis (CF) lung infections. "

08/24/2023 - "Efficacy of Ceragenins Alone and in Combinations with Antibiotics Against Multidrug-Resistant Gram Negative Pathogens from Bloodstream Infections."

10/29/2021 - "Although ceragenins show great potential as anti-cancer agents, in some tumors, effective inhibition of cancer cells proliferation requires application of ceragenins at doses within their hemolytic range. "
01/01/2020 - "Therapeutic efficiency of ceragenins against cancers may be limited by lack of their hemocompatibility when high concentrations of molecules are required to reach a desired result. "
04/24/2018 - "Natural antimicrobial peptides and ceragenins, as non-peptide amphipathic mimics, have been proposed as anti-cancer agents. "

05/02/2019 - "Use of ceragenins as a potential treatment for urinary tract infections."
05/16/2023 - "Antibacterial and Antibiofilm Activities of Ceragenins Alone and in Combination with Levofloxacin Against Multidrug Resistant Myroides spp. Clinical Isolates from Patients with Urinary Tract Infections."