kudiezi

a preparation consisting of flavonoids extracted from Ixeris sonchifolia (Bge.); improves blood circulation and prevents platelet aggregation for treatment of stroke and cardiovascular diseases

Also Known As:

Networked: 23 relevant articles (5 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Xie, Yan-Ming: 14 articles (12/2021 - 09/2012)
2.	Liao, Xing: 12 articles (07/2019 - 09/2012)
3.	Zhang, Yun-Ling: 5 articles (07/2019 - 05/2014)
4.	Zheng, Hong: 4 articles (01/2018 - 05/2014)
5.	Zeng, Xian-Bin: 4 articles (09/2014 - 09/2012)
6.	Yu, Dan-Dan: 3 articles (01/2019 - 08/2017)
7.	Liang, Xiao: 3 articles (01/2018 - 01/2017)
8.	Liu, Xuemei: 3 articles (01/2018 - 01/2017)
9.	Zhang, Yunling: 3 articles (01/2018 - 01/2017)
10.	Yang, Wei: 3 articles (09/2014 - 09/2013)

Related Diseases

1.	Ischemic Stroke 12/01/2017 - "The present study provided a useful approach for exploring the mechanism of ischemic stroke and evaluating the efficacy of Kudiezi injection or other traditional medicines." 10/01/2011 - "Kudiezi injection is safe and effective in the treatment of acute ischemic stroke." 10/01/2011 - "To study the effect and safety of Kudiezi injection on patients with acute ischemic stroke. " 10/01/2011 - "[Post-marketing re-evaluation of Kudiezi injection study on early treatment in patients with ischemic stroke]." 10/01/2011 - "Kudiezi injection plus TCM rehabilitation project of ischemic stroke showed some superiority to western medicine rehabilitation program on improving the neurological deficit and motor function. "
2.	Cerebral Infarction 12/01/2021 - "The evidence value of effectiveness demonstrated that Diemailing~® Kudiezi Injection combined with conventional western medicine improves the total effective rate of neurological deficit score and quality of daily life in the acute stage of cerebral infarction, which is superior to that in the conventional western medicine treatment group, and the level of evidence is high. " 01/01/2019 - "Randomized controlled trials( RCTs) for the treatment of acute cerebral infarction with Kudiezi Injection were screened out according to pre-established inclusion criteria and exclusion criteria. " 01/01/2019 - "[Systematic review and Meta-analysis on randomized controlled trials on effectiveness and safety of Kudiezi Injection in treatment of acute cerebral infarction]." 12/01/2016 - "This is a study based on hospital intensive monitoring to explore medication use of Diemailing Kudiezi injection(one Chinese herbal medicine injection) in real word in the patients with cerebral infarction. " 12/01/2021 - "Diemailing~® Kudiezi Injection can evidently improve the clinical symptoms and neurological deficits of fire toxin syndrome of acute cerebral infarction, and this medicine belongs to ethnic medicine. "
3.	Reperfusion Injury 12/01/2017 - "UHPLC-LTQ-Orbitrap-based metabolomics coupled with metabolomics pathway analysis method for exploring the protection mechanism of Kudiezi injection in a rat anti-ischemic cerebral reperfusion damage model." 12/15/2017 - "Improvement in cerebral ischemia-reperfusion injury through the TLR4/NF-κB pathway after Kudiezi injection in rats." 12/01/2017 - "Furthermore, on the basis of metabolic pathway analysis via metabolomics pathway analysis (MetPA), we first discovered that the protection mechanism in anti-ischemic cerebral reperfusion damage of Kudiezi injection was possibly related to the biosynthesis of phenylalanine, tyrosine, and tryptophan. "
4.	Brain Ischemia (Cerebral Ischemia) 01/05/2017 - "Kudiezi injection mitigates myocardial injury induced by acute cerebral ischemia in rats." 12/15/2017 - "Improvement in cerebral ischemia-reperfusion injury through the TLR4/NF-κB pathway after Kudiezi injection in rats."
5.	Drug-Related Side Effects and Adverse Reactions 08/01/2017 - "This study was aimed to obtain the incidence of adverse drug reaction (ADR) of Diemailing Kudiezi injection, explore its characteristics, related risk factors and application in real world. " 06/01/2017 - "All studies were assessed by using internationally recognized methodological quality assessment tools or reporting quality evaluation criteria; Meta-analysis of adverse drug reaction/adverse events (ADR/AE) of Kudiezi injection was performed by using Stata 12.0 software. " 09/01/2014 - "This study aims to assess if adverse drug reactions (ADRs) to Kudiezi injection are allergic in origin. " 12/01/2016 - "This is a protocol of intensive hospital monitoring with long follow up and large sample of Diemailing Kudiezi injection, which aims to identify adverse drug reactions(ADRs) of Diemailing Kudiezi injection, including known incidence of adverse reactions, the incidence of new adverse reactions, the incidence of various ADR symptoms and the incidence of ADR among the sub populations; clarify the clinical features of ADRs of Diemailing Kudiezi injection; explore risk factors for ADRs; and analyze their usage in real world. "

Related Drugs and Biologics

1.	kudiezi
2.	Proteins (Proteins, Gene)
3.	Carrageenan
4.	cortexin
5.	Interleukin-18 (Interleukin 18)
6.	Interleukin-10 (Interleukin 10)
7.	Interleukin-6 (Interleukin 6)
8.	Biomarkers (Surrogate Marker)
9.	Tyrosine (L-Tyrosine)
10.	Tryptophan (L-Tryptophan)

Related Therapies and Procedures

1.	Therapeutics
2.	Injections
3.	Intraperitoneal Injections
4.	Chinese Traditional Medicine (Traditional Chinese Medicine)