chrysamide B
dimeric nitrophenyl trans-epoxyamide isolated from deep-sea-derived fungus Penicillium chrysogenum SCSIO41001
Networked: 1
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Experts
| 1. | Chen, Jinhong:
1 article
(01/2021)
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| 2. | Fan, Xiaohong:
1 article
(01/2021)
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| 3. | Hao, Xiangyong:
1 article
(01/2021)
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| 4. | Hu, Xiaoling:
1 article
(01/2021)
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| 5. | Li, Junfang:
1 article
(01/2021)
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| 6. | Liu, Yonghong:
1 article
(01/2021)
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| 7. | Shi, Tao:
1 article
(01/2021)
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| 8. | Wang, Zhen:
1 article
(01/2021)
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| 9. | Zhao, Quanyi:
1 article
(01/2021)
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| 10. | Zhu, Longqing:
1 article
(01/2021)
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Related Diseases
| 1. | Neoplasms (Cancer)
01/01/2021
- " In this study, based on our previous work on the total synthesis and structure revision of the novel marine natural product Chrysamide B, a group of its derivatives were designed, synthesized, and subsequently of which the anti-cancer activity, structure-activity relationships and cellular mechanism were explored for the first time. " 01/01/2021
- " Compared with Chrysamide B, better anti-cancer performance of some derivatives against five human cancer cell lines (SGC-7901, MGC-803, HepG2, HCT-116, MCF-7) was observed, especially for compound b-9 on MGC-803 and SGC-7901 cells with the IC 50 values of 7.88 ± 0.81 and 10.08 ± 1.08 μM, respectively. "
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