HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

CAB2-015

a dopamine D3 receptor antagonist and partial agonist; inhibits oxycodone seeking and taking behavior in rats

Also Known As:

N-(4-(4-(naphthalen-1-yl)piperazin-1- yl)butyl)quinoline-3-carboxamide oxalate

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        CAB2-015: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - CAB2-015: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - CAB2-015: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - CAB2-015: 1

Experts

1.	Bi, Guo-Hua: 1 article (11/2017)
2.	Boateng, Comfort: 1 article (11/2017)
3.	Cao, Jianjing: 1 article (11/2017)
4.	Gao, Jun-Tao: 1 article (11/2017)
5.	Gardner, Eliot L: 1 article (11/2017)
6.	He, Yi: 1 article (11/2017)
7.	Newman, Amy Hauck: 1 article (11/2017)
8.	Xi, Zheng-Xiong: 1 article (11/2017)
9.	You, Zhi-Bing: 1 article (11/2017)

Related Diseases

1.	Opioid-Related Disorders (Opiate Addiction) 11/01/2017 - "In the present study, we first evaluated the reinforcing effects of oxycodone in a rat model of self-administration and then explored the potential utility of two novel high affinity dopamine D3 receptor (D3R) antagonists/partial agonists, CAB2-015 and BAK4-54, for treatment of prescription opioid abuse and dependence. "

Related Drugs and Biologics

1.	Dopamine D3 Receptors
2.	Oxycodone (Oxycontin)
3.	BAK4-54

Related Therapies and Procedures

1.	Self Administration (Administration, Self)