innate repair receptor

a heteromer of the erythropoietin receptor and the beta-common (CD131) receptor; it simultaneously activates anti-inflammatory and tissue repair pathways.

Also Known As:

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Yu, Guanling: 1 article (02/2016)
2.	Zhang, Mengyuan: 1 article (02/2016)
3.	Zhang, Wenjia: 1 article (02/2016)
4.	Brines, Michael: 1 article (11/2012)
5.	Cerami, Anthony: 1 article (11/2012)
6.	Dahan, Albert: 1 article (11/2012)
7.	Drent, Marjolein: 1 article (11/2012)
8.	Dunne, Ann: 1 article (11/2012)
9.	Grutters, Jan C: 1 article (11/2012)
10.	Heij, Lara: 1 article (11/2012)

Related Diseases

1.	Neurodegenerative Diseases (Neurodegenerative Disease) 02/15/2023 - "Human InsR, IGF1R, and IRR receptor tyrosine kinases (RTK) of the insulin receptor subfamily play an important role in signaling pathways for a wide range of physiological processes and are directly associated with many pathologies, including neurodegenerative diseases. "
2.	Neuralgia (Stump Neuralgia) 02/01/2016 - "The analgesic effect of ARA 290 is mediated by its anti-inflammatory and immunomodulatory functions, or more specifically, by targeting the innate repair receptor (IRR) to down-regulate inflammation to alleviate neuropathic pain. "
3.	Inflammation (Inflammations) 02/01/2016 - "The analgesic effect of ARA 290 is mediated by its anti-inflammatory and immunomodulatory functions, or more specifically, by targeting the innate repair receptor (IRR) to down-regulate inflammation to alleviate neuropathic pain. "
4.	Hyperalgesia 11/15/2012 - "ARA 290 (a peptide designed to activate the innate repair receptor that arrests injury and initiates cytoprotection, antiinflammation and healing) reduces allodynia in preclinical neuropathy models. "
5.	Hemolytic-Uremic Syndrome 01/01/2022 - "Targeting the innate repair receptor axis via erythropoietin or pyroglutamate helix B surface peptide attenuates hemolytic-uremic syndrome in mice."

Related Drugs and Biologics

1.	Tyrosine (L-Tyrosine)
2.	Insulin Receptor
3.	Phosphotransferases (Kinase)
4.	Peptides (Polypeptides)
5.	Erythropoietin
6.	Analgesics (Analgesic Drugs)
7.	cibinetide
8.	insulin receptor-related receptor (IRR)