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1- (5- (4- bromo- 2- chlorophenyl)furan- 2- yl)- N- ((piperidin- 4- yl)methyl)methanamine

has antimalarial activity against both asexual stages and gametocytes of Plasmodium falciparum

Also Known As:

MMV019918

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - 1-(5-(4-bromo-2-chlorophenyl)furan-2-yl)-N-((piperidin-4-yl)methyl)methanamine: 1
  - Piperidines: 17
    - 1-(5-(4-bromo-2-chlorophenyl)furan-2-yl)-N-((piperidin-4-yl)methyl)methanamine: 1

Experts

1.	Alfano, Gloria: 1 article (04/2018)
2.	Brindisi, Margherita: 1 article (04/2018)
3.	Brogi, Simone: 1 article (04/2018)
4.	Butini, Stefania: 1 article (04/2018)
5.	Caldelari, Reto: 1 article (04/2018)
6.	Campiani, Giuseppe: 1 article (04/2018)
7.	Chemi, Giulia: 1 article (04/2018)
8.	D'Alessandro, Sarah: 1 article (04/2018)
9.	Dechering, Koen J: 1 article (04/2018)
10.	Fusi, Fabio: 1 article (04/2018)

Related Diseases

1.

04/25/2018 - "MMV019918 (1, 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine) was selected from the MMV Malaria Box for its dual activity against both asexual stages and gametocytes. "
04/25/2018 - "Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues."

Related Drugs and Biologics

1.	Antimalarials (Antimalarial Agents)
2.	furan
3.	methylamine (methylammonium)