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4- ((N- (2- (dimethylamino)ethyl)acrylamido)methyl)- N- (4- methyl- 3- ((4- (pyridin- 3- yl)pyrimidin- 2- yl)amino)phenyl)benzamide

a highly selective type II PDGFRalpha kinase inhibitor

Also Known As:

CHMFL-PDGFR-159; CHMFL-PDGFRalpha-159

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide: 1
  - Pyridines: 88
    - 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide: 1

Experts

1.	Chen, Cheng: 1 article (04/2018)
2.	Hu, Zhenquan: 1 article (04/2018)
3.	Jiang, Zongru: 1 article (04/2018)
4.	Liu, Feiyang: 1 article (04/2018)
5.	Liu, Jing: 1 article (04/2018)
6.	Liu, Qingsong: 1 article (04/2018)
7.	Liu, Xiaochuan: 1 article (04/2018)
8.	Qi, Shuang: 1 article (04/2018)
9.	Qi, Ziping: 1 article (04/2018)
10.	Ren, Tao: 1 article (04/2018)

Related Diseases

1.	Pdgfra-Associated Chronic Eosinophilic Leukemia 04/25/2018 - "Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia."

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