nano-diamino-tetrac

tetraiodothyroacetic acid covalently bound to a poly(lactic-co-glycolic acid) nanoparticles

Also Known As:

(4-(4-(3-(3-(poly-2-(2-hydroxyacetotoxy))propanamido)aminopropoxy)-3,5-diiodophenoxy)-3,5-diiodophenyl) acetic acid

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Davis, Paul J: 8 articles (10/2021 - 10/2016)
2.	Lin, Hung-Yun: 7 articles (01/2020 - 10/2016)
3.	Mousa, Shaker A: 5 articles (10/2021 - 10/2016)
4.	Chin, Yu-Tang: 5 articles (01/2020 - 10/2016)
5.	Shih, Ya-Jung: 5 articles (01/2020 - 10/2016)
6.	Chen, Yi-Ru: 4 articles (01/2020 - 10/2018)
7.	Whang-Peng, Jacqueline: 4 articles (01/2020 - 10/2018)
8.	Nana, André Wendindondé: 4 articles (12/2018 - 10/2016)
9.	Sudha, Thangirala: 3 articles (10/2021 - 01/2017)
10.	Wang, Kuan: 3 articles (01/2020 - 10/2018)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2021 - "Its nano derivative, Nano-diamino-tetrac (NDAT), has anticancer properties in preclinical models, enhances radiosensitivity, and inhibits cancer cell growth in vitro after X-ray irradiation. " 10/01/2018 - "Nano-diamino-tetrac (NDAT) is a nanoparticulate derivative of tetraiodothyroacetic acid (tetrac), which exerts anticancer properties via several mechanisms and downregulates RRM2 gene expression in cancer cells. " 02/01/2017 - "Nano-diamino-tetrac (NDAT) targets a receptor on integrin αvβ3; αvβ3 is generously expressed by cancer cells and dividing endothelial cells and to a small extent by nonmalignant cells. " 02/01/2017 - "Targeted delivery of cisplatin to tumor xenografts via the nanoparticle component of nano-diamino-tetrac." 10/01/2016 - "Actions of l-thyroxine and Nano-diamino-tetrac (Nanotetrac) on PD-L1 in cancer cells."
2.	Colorectal Neoplasms (Colorectal Cancer) 12/01/2018 - "Enhancement by Nano-Diamino-Tetrac of Antiproliferative Action of Gefitinib on Colorectal Cancer Cells: Mediation by EGFR Sialylation and PI3K Activation." 10/01/2018 - "Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers." 01/01/2020 - "Nano-diamino-tetrac (NDAT) has been shown to enhance the anti-proliferative effect induced by first-line chemotherapy in various types of cancer, including colorectal cancer (CRC). "
3.	Mouth Neoplasms (Oral Cancer) 10/01/2018 - "Nano-diamino-tetrac (NDAT) inhibits PD-L1 expression which is essential for proliferation in oral cancer cells."

Related Drugs and Biologics

1.	Paclitaxel (Taxol)
2.	Integrins
3.	Thyroxine (Levothyroxine)
4.	Doxorubicin (Adriamycin)
5.	Cisplatin (Platino)
6.	Resveratrol
7.	Gefitinib (Iressa)
8.	tetraiodothyroacetic acid (TA(4))

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)