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IU1-47

an inhibitor of USP14 protein; structure in first source

Also Known As:

1-(1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(piperidin-1-yl)ethanone

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - IU1-47: 2

Experts

1.	Aboutalebi Vand Beilankouhi, Elmira: 1 article (11/2020)
2.	Ghorbani Haghjo, Amir: 1 article (11/2020)
3.	Hamzavi, Masoud: 1 article (11/2020)
4.	Kalantary-Charvadeh, Ashkan: 1 article (11/2020)
5.	Moghadami, Ali-Asghar: 1 article (11/2020)
6.	Mosayyebi, Bashir: 1 article (11/2020)
7.	Nazari Soltan Ahmad, Saeed: 1 article (11/2020)
8.	Sedghi, Hassan: 1 article (11/2020)
9.	Boselli, Monica: 1 article (11/2017)
10.	Cheng, Chialin: 1 article (11/2017)

Related Diseases

1.	Neurodegenerative Diseases (Neurodegenerative Disease) 11/24/2017 - "The capacity of this compound, IU1-47, to enhance protein degradation in cells was tested using as a reporter the microtubule-associated protein tau, which has been implicated in many neurodegenerative diseases. "
2.	Lung Neoplasms (Lung Cancer) 11/01/2020 - "To inhibit USP-14, A549 lung cancer cells were treated with USP-14 siRNA and IU1-47 (20 μM). "

Related Drugs and Biologics

1.	Small Interfering RNA (siRNA)
2.	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)