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Ile- Pro- Pro- Lys- Lys- Asn- Gln- Asp- Lys- Thr- Glu

reverses high glucose-mediated insulin resistance

Also Known As:

IPPKKNQDKTE; isoleucyl-prolyl-prolyl-lysyl-lysyl-asparagyl-glutaminyl-aspartyl-lysyl-threonyl-glutamic acid

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Dietary Proteins: 2387
    - Dietary Animal Proteins: 18
      - Milk Proteins: 847
        Caseins: 2412
        Ile-Pro-Pro-Lys-Lys-Asn-Gln-Asp-Lys-Thr-Glu: 1
  - Phosphoproteins: 1772
    - Caseins: 2412
      - Ile-Pro-Pro-Lys-Lys-Asn-Gln-Asp-Lys-Thr-Glu: 1
- Peptides: 82426
  - Peptide Fragments: 373
    - Ile-Pro-Pro-Lys-Lys-Asn-Gln-Asp-Lys-Thr-Glu: 1

Experts

1.	Chen, Bin: 1 article (01/2017)
2.	Du, Min: 1 article (01/2017)
3.	Li, Tian-Ge: 1 article (01/2017)
4.	Mao, Xue-Ying: 1 article (01/2017)
5.	Song, Jia-Jia: 1 article (01/2017)
6.	Wang, Qian: 1 article (01/2017)

Related Diseases

1.	Insulin Resistance 01/01/2017 - "IPPKKNQDKTE prevents high glucose-induced insulin resistance in HepG2 cells by modulating the IRS-1/PI3K/Akt signaling pathway through AMPK activation, indicating that IPPKKNQDKTE plays a potential role in the prevention and treatment of hepatic insulin resistance and type 2 diabetes." 01/01/2017 - "Casein glycomacropeptide-derived peptide IPPKKNQDKTE ameliorates high glucose-induced insulin resistance in HepG2 cells via activation of AMPK signaling."
2.	Type 2 Diabetes Mellitus (MODY) 01/01/2017 - "IPPKKNQDKTE prevents high glucose-induced insulin resistance in HepG2 cells by modulating the IRS-1/PI3K/Akt signaling pathway through AMPK activation, indicating that IPPKKNQDKTE plays a potential role in the prevention and treatment of hepatic insulin resistance and type 2 diabetes."

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Glucose (Dextrose)
3.	Caseins (Casein)
4.	caseinomacropeptide