asclepiasterol

reverses P-glycoprotein-mediated multidrug resistance; isolated from Asclepias curassavica; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 05/24/2016 - "These results suggest that asclepiasterol could be developed as a modulator for reversing P-gp-mediated MDR in P-gp-overexpressing cancer variants. " 05/24/2016 - "Asclepiasterol, a novel C21 steroidal glycoside derived from Asclepias curassavica, reverses tumor multidrug resistance by down-regulating P-glycoprotein expression."

1.	Member 1 Subfamily B ATP Binding Cassette Transporter
2.	Glycosides
3.	compound 21