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leiodermatolide C

an antimitotic agent isolated from the marine sponge Leiodermatium; structure in first source

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Macrolides: 4391
    - leiodermatolide C: 1
  - Polyketides: 231
    - Macrolides: 4391
      - leiodermatolide C: 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Polyketides: 231
    - Macrolides: 4391
      - leiodermatolide C: 1

Experts

1.	Guzmán, Esther A: 1 article (01/2017)
2.	Pitts, Tara P: 1 article (01/2017)
3.	Pomponi, Shirley A: 1 article (01/2017)
4.	Reed, John K: 1 article (01/2017)
5.	Roberts, Jill C: 1 article (01/2017)
6.	Wright, Amy E: 1 article (01/2017)

Related Diseases

1.	Adenocarcinoma 01/01/2017 - "It inhibits the proliferation of the AsPC-1 human pancreatic adenocarcinoma cell line with an IC50 of 43 nM. Leiodermatolide C (3) has a modified macrolide ring and is over 85-fold less potent with an IC50 of 3.7 μM against the same cell line. "

Related Drugs and Biologics

1.	Macrolides