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samoamide A

cytotoxic from American Samoan marine Cyanobacterium; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - samoamide A: 2
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - samoamide A: 2

Experts

1.	Chang, Qi: 1 article (02/2019)
2.	Li, Yu-Lei: 1 article (02/2019)
3.	Zhao, Xia: 1 article (02/2019)
4.	Armstrong, Lorene: 1 article (01/2017)
5.	Boudreau, Paul D: 1 article (01/2017)
6.	Debonsi, Hosana M: 1 article (01/2017)
7.	Dorrestein, Pieter C: 1 article (01/2017)
8.	Gerwick, William H: 1 article (01/2017)
9.	Lee, John: 1 article (01/2017)
10.	Miller, Bailey W: 1 article (01/2017)

Related Diseases

1.

Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)

01/01/2017 - "Although there was no particular selectivity between the cell lines tested for samoamide A, the most potent activity was observed against H460 human non-small-cell lung cancer cells (IC50 = 1.1 μM). "
02/01/2019 - "Samoamide A is a cyclic octapeptide rich in proline and phenylalanine residues isolated from an American Samoa marine cyanobacterium, which exhibits potent activity against H460 human non-small-cell lung cancer cells (IC50 of 1.1 μM). "

Related Drugs and Biologics

1.	Proline (L-Proline)
2.	Phenylalanine (L-Phenylalanine)