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furanyl fentanyl

a synthetic opioid; structure in first source

Also Known As:

N-(1-(2-phenylethyl)-4-piperidinyl)-N-phenylfuran-2-carboxamide; furanylfentanyl; tetrahydrofuranylfentanyl

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - furanyl fentanyl: 6
  - Piperidines: 17
    - Fentanyl: 6858
      - furanyl fentanyl: 6

Experts

1.	Bassman, Jonathon R: 1 article (01/2022)
2.	Beardsley, Patrick M: 1 article (01/2022)
3.	Hassanien, Sherif H: 1 article (01/2022)
4.	Holt, Melissa C: 1 article (01/2022)
5.	Iula, Donna M: 1 article (01/2022)
6.	Layle, Nathan K: 1 article (01/2022)
7.	Stevens, David L: 1 article (01/2022)
8.	Varshneya, Neil B: 1 article (01/2022)
9.	Akpunonu, Peter: 1 article (09/2019)
10.	Gerona, Roy: 1 article (09/2019)

Related Diseases

1.	Opiate Overdose 11/01/2016 - "The mean and median blood concentrations for U-47700 were 253 ng/mL (±150) and 247 ng/mL, respectively, range 17-490 ng/mL. The mean and median blood concentrations for furanyl fentanyl were 26 ng/mL (±28) and 12.9 ng/mL, respectively, range 2.5-76 ng/mL. Given the widespread geographical distribution and increase in prevalence in postmortem casework, toxicology testing should be expanded to include testing for "designer opioids" in cases with histories consistent with opioid overdose but with no traditional opioids present or insufficient quantities to account for death." 11/03/2017 - "Fentanyl analogs were present in >10% of opioid overdose deaths in four states, with carfentanil, furanylfentanyl, and acetylfentanyl identified most frequently. "
2.	Seizures (Absence Seizure) 09/01/2018 - "The analysis of drug seizures from the county in 2016 and 2017 demonstrated that carfentanil was the most commonly identified fentanyl analog and was most often detected in combination with heroin, fentanyl, furanyl fentanyl and/or other fentanyl analogs. "
3.	Pica (Geophagia) 11/01/2022 - "Of 88 included NPS, 34 (mitragynine, flualprazolam, 3F/4F-α-P(i)HP, etizolam, 4F-MDMB-BINACA, cyproheptadine, 5F-MDMB-PICA, isotonitazene, isohexedrone, MDPEP, N-ethylpentedrone, tianeptine, flubromazolam, 4'-methylhexedrone, α-P(i)HP, eutylone, mephedrone, N-ethylhexedrone, 5F-MDMB-PINACA, ADB-BUTINACA, 3-methoxy PCP, 4F-furanylfentanyl, 4F-isobuturylfentanyl, acrylfentanyl, furanylfentanyl, clonazolam, norfludiazepam, 3F-phenmetrazine, 3-MMC, 4-methylpentedrone, BMDP, ethylphenidate, methylone and α-PVP) were identified as 219 findings in 84 patients. "
4.	Hypoventilation 01/01/2022 - "The ED50 values for hypoventilation showed a rank order of potency as follows: fentanyl (ED50 = 0.96 mg/kg) > 3-furanylfentanyl (ED50 = 2.60 mg/kg) > crotonylfentanyl (ED50 = 2.72 mg/kg) > para-methoxyfentanyl (ED50 = 3.31 mg/kg) > buprenorphine (ED50 = 10.8 mg/kg) > isobutyrylfentanyl (ED50 = 13.5 mg/kg) > para-methoxybutyrylfentanyl (ED50 = 16.1 mg/kg) > thiophenefentanyl (ED50 = 18.0 mg/kg) > morphine (ED50 = 55.3 mg/kg) > benzodioxolefentanyl (ED50 = 10,168 mg/kg). "
5.	Apnea 09/01/2019 - "Highly potent fentanyl analogs: apnea from exposure to small quantities of ß-hydroxyfentanyl and furanylfentanyl." 09/01/2019 - "We report two cases where users developed apnea and required naloxone reversal after exposure to small quantities of the fentanyl analogs, furanylfentanyl and ß-hydroxyfentanyl. "

Related Drugs and Biologics

1.	Fentanyl (Sublimaze)
2.	carfentanil (carfentanyl)
3.	Phenmetrazine (Preludin)
4.	Naloxone (Narcan)
5.	Heroin (Diamorphine)
6.	Cyproheptadine (Periactin)
7.	Opioid Analgesics (Opioids)
8.	mephedrone
9.	methylone
10.	tianeptine (Stablon)