HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

MIV-247

a cathepsin S inhibitor; structure in first source

Also Known As:

N-(1-(2-amino-2-oxoacetyl)cyclobutyl)-2-(2,2-difluoropropanamido)-3-(1-fluorocyclopentyl)propanamide

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - MIV-247: 1

Experts

1.	Classon, Björn: 1 article (01/2016)
2.	Edenius, Charlotte: 1 article (01/2016)
3.	Grabowska, Urszula: 1 article (01/2016)
4.	Henderson, Ian: 1 article (01/2016)
5.	Hewitt, Ellen: 1 article (01/2016)
6.	Lindström, Erik: 1 article (01/2016)
7.	Malcangio, Marzia: 1 article (01/2016)
8.	Pitcher, Thomas: 1 article (01/2016)
9.	Rizoska, Biljana: 1 article (01/2016)
10.	Sahlberg, Britt-Louise: 1 article (01/2016)

Related Diseases

1.	Neuralgia (Stump Neuralgia) 01/01/2016 - "The current study evaluated the effects when combining the selective cathepsin S inhibitor MIV-247 with gabapentin or pregabalin in a mouse model of neuropathic pain. " 01/01/2016 - "Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain."
2.	Hyperalgesia 01/01/2016 - "Oral administration of MIV-247 (100-200 µmol/kg) dose-dependently attenuated mechanical allodynia by up to approximately 50% reversal when given as a single dose or when given twice daily for 5 days. " 01/01/2016 - "Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain."

Related Drugs and Biologics

1.	Gabapentin (Neurontin)
2.	Pregabalin (Lyrica)
3.	cathepsin S

Related Therapies and Procedures

1.	Oral Administration