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heliangin

has anti-inflammatory activity; isolated from Helianthus tuberosus; structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - heliangin: 3
- Lactones: 1549
  - heliangin: 3

Experts

1.	Kawano, Yasuhiro: 1 article (01/2022)
2.	Miyazaki, Hitoshi: 1 article (01/2022)
3.	Miyazaki, Koyomi: 1 article (01/2022)
4.	Saiki, Papawee: 1 article (01/2022)
5.	Yoshihara, Mizuki: 1 article (01/2022)
6.	An, BingChen: 1 article (04/2017)
7.	Bao, ZhiJun: 1 article (04/2017)
8.	Gou, HaiXin: 1 article (04/2017)
9.	Huang, YiZhi: 1 article (04/2017)
10.	Lu, XinGang: 1 article (04/2017)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2022 - "These results suggested that heliangin suppresses inflammation by inhibiting excessive NO production in macrophages and the expression of the factors leading to the development of atherosclerosis via the NF-κB signaling pathway in vascular endothelial cells. " 04/01/2017 - "Heliangin inhibited lipopolysaccharide-induced inflammation through signaling NF-κB pathway on LPS-induced RAW 264.7 cells." 04/01/2017 - "Heliangin exerted anti-inflammation effect in a xylene-induced ear swelling in BALB/C mice and carrageenan-induced paw edema model in SD rats. "
2.	Atherosclerosis 01/01/2022 - "Anti-Inflammatory Effects of Heliangin from Jerusalem Artichoke (Helianthus tuberosus) Leaves Might Prevent Atherosclerosis." 01/01/2022 - "These results suggested that heliangin suppresses inflammation by inhibiting excessive NO production in macrophages and the expression of the factors leading to the development of atherosclerosis via the NF-κB signaling pathway in vascular endothelial cells. " 01/01/2022 - "Therefore, heliangin in Jerusalem artichoke leaves could function in the prevention of atherosclerosis that is associated with heart attacks and strokes."
3.	Stroke (Strokes) 01/01/2022 - "Therefore, heliangin in Jerusalem artichoke leaves could function in the prevention of atherosclerosis that is associated with heart attacks and strokes."
4.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 02/01/2023 - "Here we demonstrated that heliangin, a natural sesquiterpene lactone, exerts favorable therapeutic responses in NPM1 mutant acute myeloid leukemia cells, with no apparent toxicity to normal hematogenous cells, by inhibiting their proliferation, inducing apoptosis, causing cell cycle arrest, and promoting differentiation. " 02/01/2023 - "Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia."
5.	Myocardial Infarction 01/01/2022 - "Therefore, heliangin in Jerusalem artichoke leaves could function in the prevention of atherosclerosis that is associated with heart attacks and strokes."

Related Drugs and Biologics

1.	Interleukin-6 (Interleukin 6)
2.	Xylenes (Xylene)
3.	Sesquiterpenes
4.	RNA Precursors (Precursor, mRNA)
5.	Proteins (Proteins, Gene)
6.	Lipopolysaccharides
7.	Ligands
8.	Lactones
9.	Carrageenan