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Carbon-20

Also Known As:

20C radioisotope; C-20 radioisotope

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Elements: 18681
  - Carbon: 10227
    - Carbon Isotopes: 74
      - Carbon Radioisotopes
        Carbon-20: 2
- Isotopes: 4944
  - Radioisotopes: 14866
    - Carbon Radioisotopes
      - Carbon-20: 2
  - Carbon Isotopes: 74
    - Carbon Radioisotopes
      - Carbon-20: 2

Experts

1.	Bielory, Brett P: 1 article (10/2010)
2.	Bielory, Leonard: 1 article (10/2010)
3.	Perez, Victor L: 1 article (10/2010)
4.	Koeffler, H Phillip: 1 article (08/2006)
5.	Lemp, Nathan: 1 article (08/2006)
6.	O'Kelly, James: 1 article (08/2006)
7.	Uskokovic, Milan: 1 article (08/2006)
8.	Vadgama, Jay: 1 article (08/2006)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2006 - "We have shown previously that 1alpha, 25-dihydroxy-21-(3-hydroxy-3-methylbutyl)vitamin D3 (Gemini) compounds, which have two side chains attached to carbon-20, had increased anti-tumor activities against breast, prostate and leukemia cell lines in comparison to 1,25(OH)2 vitamin D3. "
2.	Leukemia 08/01/2006 - "We have shown previously that 1alpha, 25-dihydroxy-21-(3-hydroxy-3-methylbutyl)vitamin D3 (Gemini) compounds, which have two side chains attached to carbon-20, had increased anti-tumor activities against breast, prostate and leukemia cell lines in comparison to 1,25(OH)2 vitamin D3. "
3.	Hypersensitivity (Allergy) 10/01/2010 - "Similar to the development of the prodrug concept for the nose and lung that led to the development of ciclesonide, a chloromethyl-ester group substitution at the carbon-20 (C-20) position of the traditional corticosteroid has led to the development of a family of potential ophthalmic corticosteroids including loteprednol etabonate that has demonstrated similar efficacy to the C-20 ketone corticosteroids in the treatment of the signs and symptoms of ocular allergies, but less likely to induce elevations in intraocular pressure (IOP) or the formation of cataracts. "
4.	Cataract (Cataracts) 10/01/2010 - "Similar to the development of the prodrug concept for the nose and lung that led to the development of ciclesonide, a chloromethyl-ester group substitution at the carbon-20 (C-20) position of the traditional corticosteroid has led to the development of a family of potential ophthalmic corticosteroids including loteprednol etabonate that has demonstrated similar efficacy to the C-20 ketone corticosteroids in the treatment of the signs and symptoms of ocular allergies, but less likely to induce elevations in intraocular pressure (IOP) or the formation of cataracts. "

Related Drugs and Biologics

1.	Prodrugs
2.	Ketones
3.	Esters
4.	Cholecalciferol (Vitamin D3)
5.	Adrenal Cortex Hormones (Corticosteroids)
6.	Loteprednol Etabonate (Alrex)
7.	ciclesonide
8.	hydroxide ion