caruifolin D

has anti-inflammatory activity; isolated from artemisia absinthium; structure in first source

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

1.	Neuroinflammatory Diseases 11/15/2015 - "Taken together, these results expanded our knowledge about the anti-neuroinflammatory and neuroprotective mechanism of Artemisia absinthium L., and also suggested that caruifolin D was a major anti-inflammatory component from Artemisia absinthium L., which might be developed as a drug candidate for neuroinflammation-related diseases. " 11/15/2015 - "Moreover, anti-inflammatory mechanism study showed that caruifolin D markedly suppressed the production of intracellular reactive oxygen species, which was an important player involved in neuroinflammation, leading to inhibitory effects on the activations of protein kinase C (PKC) and c-Jun N-terminal kinase (JNK), which were two major neuroinflammatory signaling pathways in the brains. "
2.	Asthma (Bronchial Asthma) 11/15/2015 - "This work aims to evaluate the anti-neuroinflammatory effects of natural sesquiterpene dimer caruifolin D from Artemisia absinthium L., which is an edible vegetable or traditional medicinal food in East Asia due to its sedation, anti-asthma and antipruritic effects. "

1.	JNK Mitogen-Activated Protein Kinases
2.	Reactive Oxygen Species (Oxygen Radicals)
3.	Protein Kinase C
4.	Sesquiterpenes
5.	Antipruritics