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methoxy poly(ethylene glycol)-block-poly(glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine

used to form nanoparticles for carrying doxorubicin

Also Known As:

mPEG-b-PLG-g-NID

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitro Compounds: 66
  - Nitroimidazoles: 565
    - methoxy poly(ethylene glycol)-block-poly(glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - Nitroimidazoles: 565
        methoxy poly(ethylene glycol)-block-poly(glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine: 1
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Polyglutamic Acid: 124
    - methoxy poly(ethylene glycol)-block-poly(glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine: 1
- Amino Acids: 30675
  - Acidic Amino Acids: 44
    - Glutamates: 45
      - Polyglutamic Acid: 124
        methoxy poly(ethylene glycol)-block-poly(glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine: 1
  - Dicarboxylic Amino Acids: 20
    - Glutamates: 45
      - Polyglutamic Acid: 124
        methoxy poly(ethylene glycol)-block-poly(glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine: 1

Experts

1.	Ahmad, Zaheer: 1 article (01/2016)
2.	Chen, Xuesi: 1 article (01/2016)
3.	Lv, Shixian: 1 article (01/2016)
4.	Shah, Afzal: 1 article (01/2016)
5.	Tang, Zhaohui: 1 article (01/2016)

Related Diseases

1.

Hypoxia (Hypoxemia)

01/01/2016 - "Based on these considerations, we synthesized hypoxia-responsive polymeric materials methoxy poly (ethylene glycol)-block-poly (glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine (mPEG-b-PLG-g-NID) by conjugation of the hydrophobic nitro imidazole derivative (NID)[6-(2-nitroimidazole) hexyl amine] with the pendant carboxylic group of poly (ethylene glycol)-block-poly (L-glutamic acid)(mPEG-b-PLG). "

Related Drugs and Biologics

1.	Ethylene Glycol (Monoethylene Glycol)
2.	Glutamic Acid (Glutamate)
3.	Nitroimidazoles
4.	Amines
5.	methoxypoly(ethylene glycol)-block-poly(glutamic acid)
6.	imidazole