HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

wenyang huazho tongluo

for treatment of systemic sclerosis

Also Known As:

WYHZTL formula

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Biological Products
  - Plant Preparations: 622
    - Plant Extracts: 3916
      - Chinese Herbal Drugs: 73
        wenyang huazho tongluo: 2
Pharmaceutical Preparations
- Chinese Herbal Drugs: 73
  - wenyang huazho tongluo: 2

Experts

1.	Bi, Yuefeng: 2 articles (01/2018 - 02/2016)
2.	Bian, Hua: 2 articles (01/2018 - 02/2016)
3.	Han, Li: 2 articles (01/2018 - 02/2016)
4.	Ouyang, Jingfeng: 2 articles (01/2018 - 02/2016)
5.	Yang, Lei: 2 articles (01/2018 - 02/2016)
6.	Ye, Songshan: 2 articles (01/2018 - 02/2016)
7.	Wang, Qian: 1 article (01/2018)
8.	Zang, Wenhua: 1 article (01/2018)
9.	Zhang, Chaoyun: 1 article (01/2018)
10.	Zhang, Cuiyue: 1 article (01/2018)

Related Diseases

1.

Fibrosis (Cirrhosis)

01/01/2018 - "The aim of this study is to further investigate the mechanism of anti-fibrosis of WYHZTL formula in SSc mouse model. "
02/20/2016 - "Western medicine therapies for SSc cannot produce satisfactory effects currently, while Traditional Chinese Medicine (TCM), such as the Wenyang Huazhuo Tongluo (WYHZTL) formula, a Chinese herbal decoction, has shown amazing anti-fibrosis efficacy on SSc in clinical applications. "
01/01/2018 - "Furthermore, WYHZTL-H seemed more effective than WYHZTL-M and/or XAV-939 on regulating Wnt1, β-catenin, TCF4, GSK3β, DKK1, cyclin D1, survivin, VEGF, CTGF, FN1 and collagen I/III. This present study demonstrates that WYHZTL formula has anti-fibrosis effect in Bleomycin-induced SSc mouse model in a dosage-dependent manner, and the molecular mechanism may be related to the inhibition of Wnt/β-catenin signaling pathway."

Related Drugs and Biologics

1.	Catenins
2.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
3.	Cyclin D1
4.	Collagen
5.	Survivin
6.	XAV939
7.	indium-bleomycin
8.	tongluo

Related Therapies and Procedures

1.	Therapeutics
2.	Chinese Traditional Medicine (Traditional Chinese Medicine)