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1-(2-hydroxy-3- methyl 4,5- dimethoxyphenyl)- 3- (1H- pyrrol- 2- yl)- 2- propen- 1- one

from Glycosmis pentaphylla; structure in first source

Also Known As:

glycopentalone

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Propane: 265
        1-(2-hydroxy-3- methyl 4,5-dimethoxyphenyl)-3-(1H-pyrrol-2-yl)-2-propen-1-one: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - 1-(2-hydroxy-3- methyl 4,5-dimethoxyphenyl)-3-(1H-pyrrol-2-yl)-2-propen-1-one: 2

Experts

1.	Abou-Tarboush, F M: 1 article (08/2016)
2.	Al-Anazi, F S M: 1 article (08/2016)
3.	Al-Anazi, K M: 1 article (08/2016)
4.	Al-Hemaid, F M: 1 article (08/2016)
5.	Ali, M A: 1 article (08/2016)
6.	Bhattacharjee, A: 1 article (08/2016)
7.	Farah, M A: 1 article (08/2016)
8.	Gurung, A B: 1 article (08/2016)
9.	Kim, S Y: 1 article (08/2016)
10.	Lee, J: 1 article (08/2016)

Related Diseases

1.	Neoplasms (Cancer) 08/12/2016 - "Glycopentalone isolated from Glycosmis pentaphylla (family Rutaceae) has cytotoxic and apoptosis inducing effects in various human cancer cell lines; however, its mode of action is not known. " 08/12/2016 - "Therefore, target fishing of glycopentalone using a combined approach of inverse docking and reverse pharmacophore mapping approach was used to identify potential targets of glycopentalone, and gain insight into its binding modes against the selected molecular targets, viz., CDK-2, CDK-6, Topoisomerase I, Bcl-2, VEGFR-2, Telomere:G-quadruplex and Topoisomerase II. These targets were chosen based on their key roles in the progression of cancer via regulation of cell cycle and DNA replication. "
2.	Hepatocellular Carcinoma (Hepatoma) 08/22/2015 - "Glycopentalone, a novel compound from Glycosmis pentaphylla (Retz.) Correa with potent anti-hepatocellular carcinoma activity."

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