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Ag-SP-DNC

structure in first source

Also Known As:

poly(((mu3-(5,6-eta)-kappaO2-kappaO2-(±)-(1S,2S,3R,4R)-3-carboxy-7-oxabicyclo(2.2.1)hept-5-ene-2-carboxylato)silver(I))monohydrate)

Networked: 3 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Tan, Xuejie: 3 articles (01/2021 - 10/2014)
2.	Jin, Xing: 2 articles (10/2015 - 10/2014)
3.	Zhang, Xiumei: 2 articles (10/2015 - 10/2014)
4.	Zhao, Yunxue: 2 articles (10/2015 - 10/2014)
5.	Guo, Hu: 1 article (01/2021)
6.	Jing, Weiqiang: 1 article (01/2021)
7.	Wang, Ganyu: 1 article (01/2021)
8.	Zhou, Changkuo: 1 article (01/2021)
9.	Han, Mingyong: 1 article (10/2015)
10.	Li, Senpeng: 1 article (10/2014)

Related Diseases

1.	Urinary Bladder Neoplasms (Bladder Cancer) 01/01/2021 - "The results of the present study suggested that Ag-SP-DNC elicits a strong anticancer effect against bladder cancer, and can therefore be used as a promising treatment for bladder cancer." 01/01/2021 - "The present study examined the effects and mechanisms of Ag-SP-DNC, a silver and singly-protonated dehydronorcantharidin complex, on bladder cancer in vitro and in vivo. " 01/01/2021 - "It was identified that Ag-SP-DNC suppressed cell proliferation and induced apoptosis in bladder cancer cells in vitro, a suppression associated with G0/G1 phase arrest and elevated intracellular reactive oxygen species (ROS) levels. " 01/01/2021 - "The Ag-SP-DNC-induced bladder cancer cell apoptosis was significantly decreased following treatment with a broad caspase inhibitor, zVAD-fmk. "
2.	Lung Neoplasms (Lung Cancer) 10/30/2014 - "In this study, we offer evidence that Ag-SP-DNC elicits a reactive oxygen species (ROS)-mediated mitochondrial apoptosis in lung cancer cells. " 10/15/2015 - "We have recently reported that Ag-SP-DNC, a novel silver and singly protonated dehydronorcantharidin complex, triggers oxidative stress-mediated apoptosis of lung cancer cells. "
3.	Colorectal Neoplasms (Colorectal Cancer) 10/15/2015 - "Taken together, our study demonstrates the potent anticancer effects of Ag-SP-DNC to colorectal cancer. "
4.	Carcinoma (Carcinomatosis) 10/15/2015 - "In this study, we investigated the anticancer effects of Ag-SP-DNC in CT-26 murine colon carcinoma model. "
5.	Neoplasms (Cancer) 10/15/2015 - "Ag-SP-DNC induced apoptosis of CT-26 cells, together with inhibition of cell proliferation; treatment of CT-26 tumor-bearing mice with Ag-SP-DNC delayed tumor growth. " 01/01/2021 - "In addition, treatment of MB49 tumor-bearing mice with Ag-SP-DNC significantly inhibited tumor growth and decreased the anti-apoptosis and cell cycle promotion protein levels in the tumor. "

Related Drugs and Biologics

1.	Reactive Oxygen Species (Oxygen Radicals)
2.	Silver
3.	Caspases
4.	Proteins (Proteins, Gene)
5.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone