NB-360

a BACE-1 inhibitor that blocks amyloid-beta deposition; structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

1.	Neuroinflammatory Diseases 01/01/2019 - "Furthermore, chronic animal studies with NB-360 revealed relationships between BACE-1 inhibition, Aβ deposition, and Aβ-related downstream effects on neuroinflammation, neuronal function, and markers of neurodegeneration. " 09/03/2015 - "A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice." 09/03/2015 - "The reduced neuroinflammation upon amyloid reduction by NB-360 treatment supports the notion that targeting amyloid-β pathology can have beneficial downstream effects on the progression of Alzheimer's disease."
2.	Alzheimer Disease (Alzheimer's Disease) 09/03/2015 - "The reduced neuroinflammation upon amyloid reduction by NB-360 treatment supports the notion that targeting amyloid-β pathology can have beneficial downstream effects on the progression of Alzheimer's disease."

1.	Amyloid (Amyloid Fibrils)