aerothionin
has antineoplastic activity; isolated from a Red Sea sponge of the Suberea genus; structure in first source
Networked: 2
relevant articles (1 outcomes,
0 trials/studies)
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Bio-Agent Context: Research Results
Experts
Related Diseases
1. | Neoplasms (Cancer)
05/01/2020
- " To confirm the anti-tumor activity of these bromotyrosines, 3D-pheochromocytoma cell spheroids were treated with 10 µM of either Aerothionin or Homoaerothionin, resulting in a significant reduction or even complete inhibition of the spheroid growth. " 05/01/2020
- " Anti-Tumor Activity vs. Normal Cell Toxicity: Therapeutic Potential of the Bromotyrosines Aerothionin and Homoaerothionin In Vitro." 05/01/2020
- " Our in vitro results show promise for the application of Aerothionin and Homoaerothionin as anti-tumor agents against pheochromocytomas and suggest acceptable toxicity on normal tissue cells." 05/01/2020
- " Here, we investigated the anti-tumor activity of Aerothionin and Homoaerothionin, two bromotyrosines isolated from the marine demosponge Aplysina cavernicola, on two mouse pheochromocytoma cells, MPC and MTT. " 08/05/2021
- " We have also accounted for the total synthesis of cytotoxic molecules, subereamolline A, aerothionin, asmarine B, norrsolide and latrunculin B showing interesting activity against different cancer cell lines."
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2. | Pheochromocytoma
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