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EM-E-11-4

from Euphorbia micractina; structure in first source

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - EM-E-11-4: 1

Experts

1.	Cai, Pei: 1 article (01/2020)
2.	Guo, Siwei: 1 article (01/2020)
3.	Liu, Qian: 1 article (01/2020)
4.	Shi, Jiangong: 1 article (01/2020)
5.	Sun, Hua: 1 article (01/2020)

Related Diseases

1.

Neoplasms (Cancer)

01/01/2020 - "These results suggest EM-E-11-4 may serve as a promising MDR reversal agent, particularly for patients bearing tumors with high expression of P-gp and βIII-tubulin."
01/01/2020 - "In this study, EM-E-11-4, a lathyrane-type diterpenoid extracted from Euphorbia micractina, demonstrated good anti-MDR (multidrug resistance) activity in paclitaxel-resistant tumor cells overexpressing either P-gp or βIII-tubulin. "

Related Drugs and Biologics

1.	Paclitaxel (Taxol)
2.	Tubulin
3.	Diterpenes
4.	lathyrane