tetramethylene hemicyanine

01/01/2021 - "In this work, for the first time, the authors discovered that the commonly used near-infrared (NIR) fluorogenic hemicyanine (CyNH2 ) induces pyrolysis to kill cancer cells and boost antitumor immunity. "
12/20/2019 - "Here, we developed a highly selective and ultrasensitive hemicyanine-based near-infrared (NIR) fluorescence probe (probe HCYSN) for the sensing of hNQO1 activity and discrimination of human cancer cells. "
01/01/2023 - "Intracellular Formation of Hemicyanine Nanoparticle Enhances Tumor-Targeting Photoacoustic Imaging and Photothermal Therapy."
10/10/2021 - "Dual-locking nanoprobe based on hemicyanine for orthogonal stimuli-triggered precise cancer imaging and therapy."
12/01/2022 - "Hemicyanine-based pH-responsive probes for rapid hypoxia detection in cancer cells."

01/01/2023 - "In this study, brominated hemicyanine (Hemi-Br), a photosensitizer, was loaded onto folic acid (FA)-tagged, glutathione (GSH)-coated Ag2S quantum dots (AS-GSH QDs) to provide enhanced phototoxicity via a photodynamic and mild photothermal effect in folate receptor(+) cancer cell lines at clinically relevant 640 nm irradiation. "

10/14/2020 - "In this study, we present a highly sensitive electrospun nanofibrous polyurethane wound dressing incorporating a hemicyanine-based chromogenic probe with a labile ester linkage that can be enzymatically cleaved by bacterial lipase released from clinically relevant strains, such as Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA). "

12/01/2023 - "Herein, the Near-infrared imaging of hepatocellular carcinoma (HCC) and its medicinal treatment was achieved with a γ-glutamyl transpeptidase (GGT)-monitoring fluorescence probe KYZ-GGT which consisted of the typical recognition group γ-glutamyl and the structurally modified signal reporting group hemicyanine-thioxanthene. "
11/15/2022 - "A hemicyanine-based fluorescent probe for simultaneous imaging of Carboxylesterases and Histone deacetylases in hepatocellular carcinoma."

12/01/2022 - "Hemicyanine-based pH-responsive probes for rapid hypoxia detection in cancer cells."
02/15/2022 - "The hypoxia-activated and nitroreductase-responsive phototheranostic probe has been developed by incorporating a nitro group into a hemicyanine fluorophore. "
12/01/2022 - "As pH-sensitive and hypoxia-responsive probes, three hemicyanine derivatives based on vanillin and the indole ring (Val-Hcys) were synthesized. "