VEGF Trapon

an angiogensis inhibitor with antineoplastic activity; a soluble decoy receptor derived from VEGFR-1, VEGFR-2, and IgG1

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 01/01/2015 - "These results support further clinical development of VEGF Trapon for PTC and other cancer types." 01/01/2015 - "In the intervention model, VEGF Trapon inhibited tumor growth by 68 ± 7% (p < 0.01). " 01/01/2015 - "In the prevention model, VEGF Trapon inhibited tumor growth by 73 ± 12% compared with control (p = 0.014) and significantly prolonged survival. " 01/01/2015 - "VEGF Trapon inhibits tumor growth in papillary thyroid carcinoma." 01/01/2015 - "VEGF Trapon is a potent inhibitor of BC-PAP tumor growth, angiogenesis and blocks the biological function of VEGF in vivo. "
2.	Neoplasm Metastasis (Metastasis) 01/01/2015 - "treatment with VEGF Trapon or control protein (25 mg/kg twice weekly) was started shortly after tumor injection to prevent tumor development (prevention model) or after established tumors were formed to inhibit tumor growth and metastasis formation (intervention model). "
3.	Papillary Thyroid Cancer 01/01/2015 - "VEGF Trapon inhibits tumor growth in papillary thyroid carcinoma."

1.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2.	Proteins (Proteins, Gene)